Familial Lipoprotein Disorders in Patients With Premature Coronary Artery Disease

Jacques Genest, Sarah Martin-Munley, Judith McNamara, José M. Ordovás, J L Jenner · Circulation · 1992

Summary

It is indicated that more than half of patients with premature CAD have a familial lipoprotein disorder, with Lp(a) excess, hypertriglyceridemia with hypoalphalipoproteinemia, and combined hyperlipidemia and apolipoprotein levels are in part genetically determined.

Type: article
Published: 1992-06-01
Cited by: 619
References: 53
Access: Open access
DOI: https://doi.org/10.1161/01.cir.85.6.2025
PubMed: https://pubmed.ncbi.nlm.nih.gov/1534286/
OpenAlex: https://openalex.org/W1973178110
Semantic Scholar: https://api.semanticscholar.org/CorpusID:288509

Keywords

Medicine, Internal medicine, Proband, Hypertriglyceridemia, Apolipoprotein B

References

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Metabolism of apolipoproteins A-I, A-II, and A-IV.Ernst J. Schaefer, José M. Ordovás — 1986
Familial apolipoprotein A-I, C-III, and A-IV deficiency and premature atherosclerosis due to deletion of a gene complex on chromosome 11.José M. Ordovás, D. Cassidy, Fernando Civeira — 1989
Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol.G. Russell Warnick, J Benderson, J J Albers — 1982
The mysteries of lipoprotein(a).Gerd Utermann — 1989
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Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions.Judith McNamara, Ernst J. Schaefer — 1987
Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins].Allan D. Sniderman, Stan Shapiro, D Marpole — 1980
Low Density Lipoprotein Metabolism in Familial Combined Hyperlipidemia: Mechanism of the Multiple Lipoprotein Phenotypic ExpressionAhmed H. Kissebah, S. Alfarsi, David J. Evans — 1984
Causes of High Blood CholesterolScott M. Grundy, Gloria Lena Vega — 1990
Lipoprotein cholesterol, apolipoprotein A-I and B and lipoprotein (a) abnormalities in men with premature coronary artery disease.Jacques Genest, Judith McNamara, José M. Ordovás — 1992
The Increased Risk of Death from Ischaemic Heart Disease in First Degree Relatives of 121 Men and 96 Women with Ischaemic Heart DiseaseJ. Slack, K. Evans — 1966
Clinical, biochemical, and genetic features in familial disorders of high density lipoprotein deficiency.Ernst J. Schaefer — 1984
DNA polymorphisms of the apolipoprotein B gene in patients with premature coronary artery disease.J GENESTJR, José M. Ordovás, Judith McNamara — 1990

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Lipoprotein disorders and cardiovascular riskVernon L. Smith, James T. Walker — 2003
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Circulating C5L2 gene polymorphism is associated with type 2 diabetes mellitus in Saudi population裕夫大下 — 2013
Decreased circulating Fas ligand in patients with familial combined hyperlipidemia or carotid atherosclerosis: normalization by atorvastatin.Luis Miguel Blanco‐Colio, José Luis Martín‐Ventura, J. M. Sol — 2004
Lipoprotein(a) – Einfluss auf die kardiovaskuläre ManifestationKlaus‐Peter Mellwig, Cornelia Schatton, B. Biermann — 2015
Lipoprotein(a) interactions with lipid and non-lipid risk factors in patients with early onset coronary artery disease: results from the NHLBI Family Heart Study.Paul N. Hopkins, Steven C. Hunt, Pamela J. Schreiner — 1998
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[Familial hypercholesterolemia: epidemiology, genetics, diagnosis, and screening].Sinan Üy, Sansoy — 2014
HIGH DENSITY LIPOPROTEIN: GUARDIAN OF THE VASCULAR SYSTEM?C.J. Packard, Alistair V.W. Nunn, Richard Hobbs — 2002
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Familial Lipoprotein Disorders in Patients With Premature Coronary Artery Disease

Summary

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