ATP-Dependent histone octamer mobilization and histone deacetylation mediated by the Mi-2 chromatin remodeling complex.

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Summary

A purified Mi-2 complex containing six components is used to investigate the capacity of this complex to destabilize histone-DNA interactions and deacetylate core histones and Surprisingly, ATPase activity had no effect on de acetylation of nucleosomal arrays.

Type
article
Published
2000-04-13
Cited by
93
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0

Keywords

Histone octamer, Nucleosome, Histone, Chromatin structure remodeling (RSC) complex, Acetylation

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