Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.

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Summary

Neocortical neurofibrillary tangle densities were substantially correlated with dementia severity, and to a greater degree than was true for senile plaque densities, and the order of the strength of relationships between densities of histologic markers and dementia severity in AD is neuroFibrillary tangles greater than cored senile plaques greater than total senile Plaques.

Type
article
Published
1998-03-01
Cited by
670
References
94

Keywords

Senile plaques, Neurofibrillary tangle, Dementia, Alzheimer's disease, Pathology

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