An oral controlled release matrix pellet formulation containing nanocrystalline ketoprofen.

Keywords

Ketoprofen, Pellet, Microcrystalline cellulose, Maltodextrin, Chemical engineering

References

• Nanosuspensions for the formulation of poorly soluble drugs: I. Preparation by a size-reduction techniqueRainer H Müller, Katrin Peters — 1998
• Development of Controlled Release Formulations of Ketoprofen for Oral UseMuhammad J. Habib, Roland Mesue — 1995
• A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discsPhilip L. Ritger, Nikolaos A. Peppas — 1987
• Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in ratsGary G. Liversidge, Phil Conzentino — 1995
• Matrix pellets based on the combination of waxes, starches and maltodextrinsXuechang Zhou, Chris Vervaet, J.P. Remon — 1996
• In vivo evaluation of rapid release and sustained release Gelucire capsule formulationsA.B. Dennis, Stephen J. Farr, I.W. Kellaway — 1990
• Wettability of a hydrophobic drug by surfactant solutionsPaul E. Luner, S. Babu, Surendra C. Mehta — 1996

Cited by

• Desenvolvimento e caracterização de comprimidos matriciais de dupla camada contendo ParacetamolJosé Pedro Machado Liberal — 2009
• Conformational study of ketoprofen by combined DFT calculations and Raman spectroscopy.Edgar E. Feige — 2006
• The effect of the ratio of two acrylic polymers on the in vitro release kinetics of ketoprofen from pellets prepared by extrusion and spheronisation technique.Golam Kibria, Reza Ul-Jalil — 2008
• Pellets formulation of crystalline nanoparticles. A formulation process and characterization study.Patrik Träff — 2011
• NANOSUSPENSION TECHNOLOGY: A INNOVATIVE SLANT FOR DRUG DELIVERY SYSTEM AND PERMEABILITY ENHANCER FOR POORLY WATER SOLUBLE DRUGSDhiren P. Shah, B. G. Patel, Chainesh Shah — 2015
• Nanocrystal formulation for poorly soluble drugsPeng Liu — 2013
• Nanosuspension technologies for delivery of poorly soluble drugsRoya Yadollahi, Krasimir Vasilev, Spomenka Simović — 2015
• SELF EMULSIFYING DRUG DELIVERY SYSTEM: A CONVENTIONAL ANDALTERNATIVE APPPROACH TO IMPROVE ORAL BIOAVAILABILITY OFLIPOPHILIC DRUGSPatel Vipul P. Desai Tushar R, Pankaj Kapupara, Atara Samir A — 2010
• Self Emulsifying Drug Delivery System: A Gentle Approach for drug deliveryAnoop P. Patel, Neha Sharma, Anoop Kumar — 2013
• Properties of spherical pellets produced by a hot-melt extrusion and spheronization processChristopher R. Young — 2004
• Preparation and in vitro/in vivo evaluation of a ketoprofen orally disintegrating/sustained release tabletQionghua Wei, Feifei Yang, Libiao Luan — 2013
• Ketoprofen Spray-dried Microspheres Based on Eudragit® RS and RL: Study of the Manufacturing ParametersGiovanna Rassu, Elisabetta Gavini, Gianpiera Spada — 2008
• Colon-specific drug delivery: Influence of solution reticulation properties upon pectin beads performance.Odile Chambin, Gilles Dupuis, Dominique Champion — 2006
• Development and in vitro evaluation of an enteric-coated multiparticulate drug delivery system for the administration of piroxicam to dogs.Ann Debunne, Chris Vervaet, Jean‐Paul Remon — 2002
• Improved oral bioavailability of core-shell structured beads by redispersion of the shell-forming nanoparticles: preparation, characterization and in vivo studies.Qing Yao, Xiaoguang Tao, Bin Tian — 2014
• Solubility enhancement of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) using polypolypropylene oxide core PAMAM dendrimers.Fatma Koç, Mehmet Şenel — 2013
• What are parameters affecting Leu-enkephalin loading and release from poly(isobutylcyanoacrylate) nanoparticles coated with thiolated chitosan?Silvia Mazzaferro, Kawthar Bouchemal, Christine Vauthier — 2011
• Preparation and characterization of ketoprofen-loaded solid lipid nanoparticles made from beeswax and carnauba wax.Soheila Kheradmandnia, Ebrahim Vasheghani‐Farahani, Mohsen Nosrati — 2010
• Factors influencing the release kinetics of drug nanocrystal-loaded pellet formulationsJan P. Möschwitzer, Rainer Müller — 2013
• Preparation of sustained release matrix pellets by melt agglomeration in the fluidized bed: influence of formulation variables and modelling of agglomerate growth.Anette Pauli-Bruns, Klaus Knop, B. Lippold — 2010

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