Nanoengineered analytical immobilized metal affinity chromatography stationary phase by atom transfer radical polymerization: separation of synthetic prion peptides.

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Summary

The column was capable of separating prion-related peptides differing in number of octapeptide repeat units, and could also resolve peptides containing the same number of repeats but differing only in the presence of a hydrophilic tail, Q-->A substitution, or amide nitrogen methylation.

Type
article
Published
2007-07-01
Cited by
21
References
48
Access
Open access

Keywords

Chemistry, Polymerization, Peptide, Nanoparticle, Affinity chromatography

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