Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis
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Summary
The observations suggest that MSCs are already multidifferentiated and that neural differentiation comprises quantitative modulation of gene expression rather than simple on–off switching of neural‐specific genes.
- Type
- article
- Published
- 2002-09-15
- Cited by
- 478
- References
- 59
- Access
- Open access
- OpenAlex
- https://openalex.org/W1970865563
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31101929
Keywords
Biology, Mesenchymal stem cell, Cell biology, Neurogenesis, Stem cell
References
- Mesenchymal Stem Cells
- Primary structure of rat ceruloplasmin and analysis of tissue-specific gene expression during development.
- Precursor cells of mechanocytes.
- Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact.
- Skeletal myogenic potential of human and mouse neural stem cells
- Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow.
- Expression of neuron-specific tubulin defines a novel population in the proliferative layers of the developing telencephalon
- TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth
- Stem Cell Plasticity in Mammals and Transdetermination in Drosophila: Common Themes?
- From marrow to brain: expression of neuronal phenotypes in adult mice.
- Loops, lineage, and leukemia.
- Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein.
- On the track of a human circulating mesenchymal stem cell of neural crest origin.
- The structure of the brain-specific rat aldolase C gene and its regional expression.
- Factors required for bone marrow stromal fibroblast colony formation in vitro
- Adult bone marrow stromal cells differentiate into neural cells in vitro.
- Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia.
- Use of mesenchymal stem cells in a collagen matrix for achilles tendon repair
- NeuroD and neurogenesis.
- Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos.
Cited by
- The effects of neuronal induction on gene expression profile in bone marrow stromal cells (BMSC)--a preliminary study using microarray analysis.
- Neuron-like differentiation of adipose tissue-derived stromal cells and vascular smooth muscle cells.
- Analysis of neural potential of human umbilical cord blood–derived multipotent mesenchymal stem cells in response to a range of neurogenic stimuli
- In Vitro and In Vivo Characterization of Neurally Modified Mesenchymal Stem Cells Induced by Epigenetic Modifiers and Neural Stem Cell Environment
- Stem cells and spinal cord injury repair.
- Differentiation Potential of Human Bone Marrow Mesenchymal Stem Cells into Motorneuron-like Cells on Electrospun Gelatin Membrane
- Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism
- Toward reprogramming cells to pluripotency.
- Autotransplantation of bone marrow-derived stem cells as a therapy for neurodegenerative diseases.
- "Stem cells into liver"--basic research and potential clinical applications.
- Adipose-Derived Stem Cell Osteogenic Differentiation: A Study of the Influence of Extracellular Matrix on the Differentiation Process
- Isolation of stromal stem cells from human adipose tissue.
- Cytotoxic and Genotoxic effects of Arsenic and Lead on Human Adipose Derived Mesenchymal Stem Cells (AMSCs)
- DIFFERENTIATION OF EQUINE MESENCHYMAL STROMAL CELLS INTO CELLS OF NEURAL LINEAGE AND THEIR APPLICATION INTO A NOVEL MODEL FOR ACUTE PERIPHERAL NERVE INJURY IN THE HORSE
- Mesenchymal stem cells as trophic mediators of neural differentiation
- Cysteine: A Novel Neural Inducer for Rat Bone Marrow Mesenchymal Stem Cells
- Using stem cells to repair the degenerate retina. Stem cells in the context of retinal degenerations.
- ANÁLISE MOLECULAR E CITOQUÍMICA DE GENES E PROTEÍNAS RELACIONADOS A OSTEODIFERENCIAÇÃO EM CÉLULAS TRONCO DERIVADAS DO TECIDO ADIPOSO.
- Neural stem cells in the mammalian brain.
- Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells into Neurocytes and Adipocytes Induced in vitro
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