Mitosis: shutting the door behind when you leave.
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Summary
A pathway has been identified, involving a small GTPase, which prevents the onset of cytokinesis until one of the spindle poles has migrated into the bud.
- Type
- review
- Published
- 2000-11-01
- Cited by
- 5
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W1970484403
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34733303
Keywords
Biology, Cytokinesis, Mitosis, Cell biology, Mitotic exit
References
- Anaphase spindle position is monitored by the BUB2 checkpoint
- Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
- A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein
- Regulation of the APC and the exit from mitosis
- The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase
- The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation.
- Phosphorylation and spindle pole body localization of the Cdc15p mitotic regulatory protein kinase in budding yeast.
- Eb1 Proteins Regulate Microtubule Dynamics, Cell Polarity, and Chromosome Stability
- The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit.
- The role of the Sid1p kinase and Cdc14p in regulating the onset of cytokinesis in fission yeast
- A Bub2p‐dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast
- Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex.
- Chromosome segregation: dual control ensures fidelity.
- A mechanism for coupling exit from mitosis to partitioning of the nucleus.
- Byr4 and Cdc16 form a two-component GTPase-activating protein for the Spg1 GTPase that controls septation in fission yeast.
- Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex.
- Cytokinesis in eukaryotes: a mechanistic comparison.
- The spindle checkpoint of Saccharomyces cerevisiae responds to separable microtubule-dependent events.
- Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinase.
- A Family of Putative Tumor Suppressors Is Structurally and Functionally Conserved in Humans and Yeast*
Cited by
- SEPH, a Cdc7p orthologue from Aspergillus nidulans, functions upstream of actin ring formation during cytokinesis
- Functional characterization of Rho family small GTPases in Fusarium graminearum.
- Septation and cytokinesis in fungi.
- The Tem1 small GTPase controls actomyosin and septin dynamics during cytokinesis.
- Comparison of morphogenetic networks of filamentous fungi and yeast.
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- The Surveillance Mechanism of the Spindle Position Checkpoint in Yeast
- Three-dimensional electron microscopy analysis of ndc10-1 mutant reveals an aberrant organization of the mitotic spindle and spindle pole body defects in Saccharomyces cerevisiae.
- Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit
- ANKRD53 interacts with DDA3 and regulates chromosome integrity during mitosis.