Lovastatin Downregulates Renal Myofibroblast Function in vitro

Keywords

Lovastatin, Myofibroblast, Medicine, Fibrosis, Pathology

References

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• Human skin fibroblasts in vitro differentiate along a terminal cell lineage.Klaus Bayreuther, H. Peter Rodemann, R. Hommel — 1988
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• Renal Myofibroblasts Contract Collagen I Matrix Lattices in vitroKristen J. Kelynack, Tim D. Hewitson, Eugenia Pedagogos — 1999
• Fluvastatin suppresses oxidative stress and fibrosis in the interstitium of mouse kidneys with unilateral ureteral obstruction.Toshiki Moriyama, Noritaka Kawada, Katsuyuki Nagatoya — 2001
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Cited by

• Fibroblast differentiation in wound healing and fibrosis.Ian A. Darby, Tim D. Hewitson — 2007
• Impact of Statin Treatment on 1-Year Functional and Histologic Renal Allograft OutcomeRosemary Masterson, Tim D. Hewitson, Murray Leikis — 2005
• Interleukin 4 Co-Stimulates the PDGF-BB- and bFGF-Mediated Proliferation of Mesangial Cells and MyofibroblastsManfred Sommer, Ulrike Eismann, Jens Gerth — 2002
• Inhibition of pancreatic stellate cell activation by the hydroxymethylglutaryl coenzyme A reductase inhibitor lovastatin.Robert Jaster, Peter Brock, Gisela Sparmann — 2003
• The multifunctional role of fibroblasts during wound healing in Hirudo medicinalis (Annelida, Hirudinea)Gianluca Tettamanti, Annalisa Grimaldi, Liliana Rinaldi — 2004
• Effect of Inhibition of Farnesylation and Geranylgeranylation on Renal Fibrogenesis in vitroRosemary Masterson, Kristen J. Kelynack, Tim D. Hewitson — 2005
• Lovastatin inhibits TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.Tobias Meyer‐ter‐Vehn, Barbara Katzenberger, Ho Jae Han — 2008
• The dyslipidemia of chronic renal disease: effects of statin therapyR.C. Özsoy, Sander I. van Leuven, John J.P. Kastelein — 2006
• Fluvastatin Reduces Renal Fibroblast Proliferation and Production of Type III Collagen: Therapeutic Implications for Tubulointerstitial FibrosisHidekazu Ikeuchi, Takashi Kuroiwa, Shin Yamashita — 2004
• EFFECT OF ATORVASTATI & SIMVASTATI OWOUD HEALIG IALBIO RATSPatil Pa, Swami T, Singh Kr — 2009
• Cell-populated floating collagen lattices: an in vitro model of parenchymal contraction.Kristen J. Kelynack — 2009
• Simvastatin Modulates Extracellular Matrix Assembly by Displaying an Antifibrotic Activity in VitroAnnele Sainio, Asta Laiho, Hannu Järveläinen — 2019
• Molecular Developments in the Treatment of Renal FibrosisG. Becker, T. Hewitson — 2005

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