A Review of Doripenem for the Treatment of Serious Bacterial Infections
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Summary
Doripenem may represent a valuable option when carbapenem therapy is warranted for the treatment of serious infection, particularly in cases in which the etiology is a drug-resistant, Gram-negative pathogen.
- Type
- review
- Published
- 2010-06-25
- Cited by
- 0
- References
- 118
- OpenAlex
- https://openalex.org/W1970338353
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52229373
Keywords
Doripenem, Intensive care medicine, Medicine, Microbiology, Antibiotics
References
- Delayed resistance selection for doripenem when passaging Pseudomonas aeruginosa isolates with doripenem plus an aminoglycoside.
- Mutant Prevention Concentrations of Doripenem and Meropenem Alone and in Combination with Colistin (Polymyxin E), Levofloxacin and Tobramycin in Pseudomonas aeruginosa
- Doripenem (Doribax): The Newest Addition to the Carbapenems
- Doripenem: A new carbapenem antibiotic a review of comparative antimicrobial and bactericidal activities
- Addressing resistance evolution in Pseudomonas aeruginosa using pharmacodynamic modelling: application to meropenem dosage and combination therapy.
- A novel 1 beta-methylcarbapenem antibiotic, S-4661. Synthesis and structure-activity relationships of 2-(5-substituted pyrrolidin-3-ylthio)-1 beta-methylcarbapenems.
- Doripenem: an expected arrival in the treatment of infections caused by multidrug-resistant Gram-negative pathogens
- In Vitro Activity of Doripenem, a Carbapenem for the Treatment of Challenging Infections Caused by Gram-Negative Bacteria, against Recent Clinical Isolates from the United States
- Comparative activity of doripenem and three other carbapenems tested against Gram-negative bacilli with various beta-lactamase resistance mechanisms.
- Newer beta-lactam antibiotics: doripenem, ceftobiprole, ceftaroline, and cefepime.
- Safety profile of meropenem: a review of nearly 5,000 patients treated with meropenem.
- Pharmacokinetic-pharmacodynamic modeling to support doripenem dose regimen optimization for critically ill patients.
- Potency of Carbapenems for the Prevention of Carbapenem-Resistant Mutants of Pseudomonas aeruginosa
- Pharmacokinetic-pharmacodynamic target attainment analysis of doripenem in infected patients.
- Concentrations in plasma, urinary excretion and bactericidal activity of levofloxacin (500 mg) versus ciprofloxacin (500 mg) in healthy volunteers receiving a single oral dose.
- Pharmacokinetics, Safety, and Tolerability of Doripenem After 0.5‐, 1‐, and 4‐Hour Infusions in Healthy Volunteers
- Pharmacodynamic assessment of doripenem in peritoneal fluid against Gram-negative organisms: use of population pharmacokinetic modeling and Monte Carlo simulation.
- Resolution of ventilator-associated pneumonia: Prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome*
- Non-susceptibility trends and serotype distributions among Streptococcus pneumoniae from community-acquired respiratory tract infections and from bacteraemias in the UK and Ireland, 1999 to 2007.
- Safety profile of meropenem: an updated review of over 6,000 patients treated with meropenem.
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