Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles.

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Summary

The physicochemical and biological characterization of cyclodextrin-containing polycations (CDP) and their nanoparticles formed with nucleic acids including plasmid DNA (pDNA) and small interfering RNA (siRNA) are described and insights can be applied to the design of targeted nucleic acid delivery vehicles in general.

Type
article
Published
2007-02-28
Cited by
268
References
27
Access
Open access

Keywords

Chemistry, Nucleic acid, Biophysics, Small interfering RNA, Ethylene glycol

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