The role of exendin-4-conjugated superparamagnetic iron oxide nanoparticles in beta-cell-targeted MRI.
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Summary
A targeted superparamagnetic iron oxide (SPIO) nanoparticle using GLP-1 analog-exendin-4 which is conjugated to polyethylene glycol coated SPIO (PEG-SPIO).
- Type
- article
- Published
- 2013-07-01
- Cited by
- 37
- References
- 26
- OpenAlex
- https://openalex.org/W1970025594
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3020087
Keywords
In vivo, Biodistribution, Materials science, Molecular imaging, Insulinoma
References
- Detection of viability of transplanted beta cells labeled with a novel contrast agent - polyvinylpyrrolidone-coated superparamagnetic iron oxide nanoparticles by magnetic resonance imaging.
- Noninvasive imaging of pancreatic β cells
- GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging.
- 18F-radiolabeled analogs of exendin-4 for PET imaging of GLP-1 in insulinoma
- Labeling transplanted mice islet with polyvinylpyrrolidone coated superparamagnetic iron oxide nanoparticles for in vivo detection by magnetic resonance imaging
- Glucagon-like peptide-1 receptor imaging for localization of insulinomas.
- Neurofunctional imaging of the pancreas utilizing the cholinergic PET radioligand [18F]4-fluorobenzyltrozamicol
- Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo.
- 68Ga-labelled exendin-3, a new agent for the detection of insulinomas with PET
- PEG-Mediated Synthesis of Highly Dispersive Multifunctional Superparamagnetic Nanoparticles: Their Physicochemical Properties and Function In Vivo
- Iron oxide nanoparticles for targeted cancer imaging and diagnostics.
- Sulfonylurea receptor as a target for molecular imaging of pancreas beta cells with 99mTc-DTPA-glipizide
- Magnetic Nanoparticles in Magnetic Resonance Imaging and Diagnostics
- Imaging Islets Labeled With Magnetic Nanoparticles at 1.5 Tesla
- Evaluation of an [18F]AlF-NOTA Analog of Exendin-4 for Imaging of GLP-1 Receptor in Insulinoma
- Glucagon-like peptide-1, glucose homeostasis and diabetes.
- Development and Evaluation of 18F-TTCO-Cys40-Exendin-4: A PET Probe for Imaging Transplanted Islets
- Glucagon-like peptide-1 receptor imaging with [Lys40(Ahx-HYNIC-99mTc/EDDA)NH2]-exendin-4 for the detection of insulinoma
- Noninvasive diagnosis of focal hyperinsulinism of infancy with [18F]-DOPA positron emission tomography.
- 11C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls
Cited by
- Novel Positively Charged Nanoparticle Labeling for In Vivo Imaging of Adipose Tissue-Derived Stem Cells
- Labeling of islet cells with iron oxide nanoparticles through DNA hybridization for highly sensitive detection by MRI.
- Bcl-2-functionalized ultrasmall superparamagnetic iron oxide nanoparticles coated with amphiphilic polymer enhance the labeling efficiency of islets for detection by magnetic resonance imaging
- A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition
- One-step hydrothermal synthesis of Fe3O4@C nanoparticles with great performance in biomedicine.
- Preparation of polylysine-modified superparamagnetic iron oxide nanoparticles
- Theranostic MRI: the future for Type 1 diabetes management?
- GLP-1R–Targeting Magnetic Nanoparticles for Pancreatic Islet Imaging
- The labeling of stem cells by superparamagnetic iron oxide nanoparticles modified with PEG/PVP or PEG/PEI.
- Application of nanomaterials for imaging pancreatic islets
- Combined toxicity of Fe3O4 nanoparticles and cadmium chloride in mice.
- Development of fluorescence-conjugated islet-homing peptide using biopanning for targeted optical imaging of pancreatic islet
- MRI-sensitive contrast agent with anticoagulant activity for surface camouflage of transplanted pancreatic islets.
- Advances in micro- and nanotechnologies for the GLP-1-based therapy and imaging of pancreatic beta-cells
- Application of Nano-biotechnology for Improvement in Therapeutic Approaches for the Treatment of Diabetes
- Squalene-PEG-Exendin as High-Affinity Constructs for Pancreatic Beta-Cells.
- Exendin‐4 analogs in insulinoma theranostics
- Nanomedicine-based Strategies for Diabetes: Diagnostics, Monitoring and Treatment
- Targeted pancreatic beta cell imaging for early diagnosis.
- Exendin-4-Conjugated Manganese Magnetism-Engineered Iron Oxide Nanoparticles as a Potential Magnetic Resonance Imaging Contrast Agent for Tracking Transplanted β-Cells
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