Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS
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Summary
An extraordinarily large number of latently infected CD4+ lymphocytes and macrophages are discovered throughout the lymphoid system from early to late stages of infection, and the extracellular association of HIV with follicular dendritic cells is confirmed.
- Type
- article
- Published
- 1993-03-25
- Cited by
- 1,483
- References
- 19
- OpenAlex
- https://openalex.org/W1969899610
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4235030
Keywords
Immune system, Biology, Immunology, Virology, Lymphatic system
References
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- The molecular biology of human immunodeficiency virus type 1 infection.
Cited by
- Activation of virus replication after vaccination of HIV-1-infected individuals
- Viral dynamics in human immunodeficiency virus type 1 infection
- The role of surface CD4 in HIV-induced apoptosis.
- Understanding HIV1, cytokines and effective immunity: bridging the gap between cytokine regulation in vitro and in vivo.
- Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1.
- Management of antiretroviral drug therapy in human immunodeficiency virus infection.
- An autoregulated dual-function antitat gene for human immunodeficiency virus type 1 gene therapy
- An Individual with a High Prevalence of a Tat-Defective Provirus in Peripheral Blood
- Viral load and immunophenotype of cells obtained from lymph nodes by fine needle aspiration as compared with peripheral blood cells in HIV-infected patients.
- Human Immunodeficiency Virus Infection of Human Bone Derived Cells
- Abrogation of in vitro suppression of human immunodeficiency virus type 1 (HIV-1) replication mediated by CD8+ T lymphocytes of asymptomatic HIV-1 carriers by staphylococcal enterotoxin B and phorbol esters through induction of tumor necrosis factor alpha
- Apoptotic killing of CD4+ T lymphocytes in HIV-1-infected PHA-stimulated PBL cultures is mediated by CD8+ LAK cells.
- Herpesvirus Saimiri Transformation of HIV Type 1 Suppressive CD8+ Lymphocytes from an HIV Type 1-Infected Asymptomatic Individual
- Analysis of Virologic and Immunologic Events in HIV Infection
- Infection with dual-tropic human immunodeficiency virus type 1 variants associated with rapid total T cell decline and disease progression in injection drug users.
- Human Immunodeficiency Virus Induces a Dual Regulation of Bcl-2, Resulting in Persistent Infection of CD4+ T- or Monocytic Cell Lines
- HIV-1 Vpr: G2 cell cycle arrest, macrophages and nuclear transport.
- Tissue Sites of Persistent Infection and Active Replication of Equine Infectious Anemia Virus during Acute Disease and Asymptomatic Infection in Experimentally Infected Equids
- High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys
- Despite high concordance, distinct mutational and phenotypic drug resistance profiles in human immunodeficiency virus type 1 RNA are observed in gastrointestinal mucosal biopsy specimens and peripheral blood mononuclear cells compared with plasma.
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