Structural Analysis of How Podocytes Detach from the Glomerular Basement Membrane Under Hypertrophic Stress
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Summary
This process in the rat after growth stimulation with FGF-2 developed various changes that could either be interpreted showing progressing stages in detachment from the GBM or stages leading to a tighter attachment by foot process effacement (FPE).
- Type
- article
- Published
- 2014-10-06
- Cited by
- 51
- References
- 59
- Access
- Open access
- OpenAlex
- https://openalex.org/W1969526333
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5830386
Keywords
Podocyte, Glomerular basement membrane, Muscle hypertrophy, Basement membrane, Hyperplasia
References
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- Cytoskeletal changes in podocytes associated with foot process effacement in Masugi nephritis.
- Pathogenesis of polycation-induced alterations ("fusion") of glomerular epithelium.
- The podocyte's response to stress: the enigma of foot process effacement.
- Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in novel mouse models with fluorescent lineage tags
- A proposed taxonomy for the podocytopathies: a reassessment of the primary nephrotic diseases.
- Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury
- The structural relationship between mesangial cells and basement membrane of the renal glomerulus
- Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis.
- Glomerular diseases seen with cancer and chemotherapy: a narrative review.
- Histological heterogeneity of glomerular segmental lesions in focal segmental glomerulosclerosis
- Long-term treatment of rats with FGF-2 results in focal segmental glomerulosclerosis.
- Glomerular podocyte vacuolation in idiopathic membranous glomerulonephritis.
- Renoprotection by Continuous Erythropoietin Receptor Activator in Puromycin Aminonucleoside-Induced Nephrotic Syndrome
Cited by
- The safety of isotretinoin in patients with lupus nephritis: a comprehensive review
- Podocyte injury and its consequences.
- Secondary Focal Segmental Glomerulosclerosis: From Podocyte Injury to Glomerulosclerosis
- Mechanical challenges to the glomerular filtration barrier: adaptations and pathway to sclerosis
- Anti-TGF-β Antibody, 1D11, Ameliorates Glomerular Fibrosis in Mouse Models after the Onset of Proteinuria
- Podocyte–actin dynamics in health and disease
- The long journey through renal filtration: new pieces in the puzzle of slit diaphragm architecture
- Acute podocyte injury is not a stimulus for podocytes to migrate along the glomerular basement membrane in zebrafish larvae
- Potential relevance of shear stress for slit diaphragm and podocyte function.
- The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier
- Epithelial-mesenchymal Transition of Glomerular Podocytes: Implications in Proteinuria
- Combined use of electron microscopy and intravital imaging captures morphological and functional features of podocyte detachment
- Focal segmental glomerulosclerosis; why does it occur segmentally?
- Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy
- Response of Renal Podocytes to Excessive Hydrostatic Pressure: a Pathophysiologic Cascade in a Malignant Hypertension Model
- Glomerular Endothelial Cell Stress and Cross-Talk With Podocytes in Early Diabetic Kidney Disease
- Novel Microscopic Techniques for Podocyte Research
- Morphological Processes of Foot Process Effacement in Puromycin Aminonucleoside Nephrosis Revealed by FIB/SEM Tomography.
- Growth hormone induces mitotic catastrophe of podocytes and contributes to proteinuria
- Role of new podocyte-associated proteins in the renal ultrafiltration barrier
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