Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data
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Summary
Because the main meta-analysis showed only a small significant survival benefit in favour of chemotherapy, the routine use of chemotherapy is debatable and for larynx preservation, the non-significant negative effect of chemotherapy in the organ-preservation strategy indicates that this procedure must remain investigational.
- Type
- article
- Published
- 2000-03-01
- Cited by
- 2,309
- References
- 16
- OpenAlex
- https://openalex.org/W1968768545
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23917537
Keywords
Meta-analysis, Medicine, Head and neck cancer, Head and neck, Chemotherapy
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- Glutathione‐associated enzymes in head and neck squamous cell carcinoma and response to cisplatin‐based neoadjuvant chemotherapy
- Treatment results and prognostic factors of advanced T3--4 laryngeal carcinoma: the University of California, San Francisco (UCSF) and Stanford University Hospital (SUH) experience.
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- Head and neck cancer: reduce and integrate for optimal outcome
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