Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue
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Summary
Protein export signals from the low‐passage 297 strain of Borrelia burgdorferi were cloned as fusions with an Escherichia coli alkaline phosphatase (PhoA) reporter lacking a signal sequence to demonstrate that at least one member of the B. burgdoferi lipoprotein family appears to be expressed only during infection.
- Type
- article
- Published
- 1995-11-01
- Cited by
- 168
- References
- 54
- OpenAlex
- https://openalex.org/W1968758915
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7996822
Keywords
Biology, Borrelia burgdorferi, Antiserum, Molecular biology, Gene
References
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- Antigenic stability of Borrelia burgdorferi during chronic infections of immunocompetent mice
- Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution
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- Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy
- The complete general secretory pathway in gram-negative bacteria.
- Chronic Lyme borreliosis in the laboratory mouse.
- Partial destruction of Borrelia burgdorferi within ticks that engorged on OspE- or OspF-immunized mice
- The cryptic ospC gene of Borrelia burgdorferi B31 is located on a circular plasmid
- The spirochetal etiology of Lyme disease.
- Megabase-sized linear DNA in the bacterium Borrelia burgdorferi, the Lyme disease agent.
- Antigenic Variability of Borrelia burgdorferi
- Distinct patterns of protective antibodies are generated against Borrelia burgdorferi in mice experimentally inoculated with high and low doses of antigen.
Cited by
- Immune evasion by tickborne and host-adapted Borrelia burgdorferi.
- Musculoskeletal manifestations of Lyme arthritis.
- Analysis of Promoter Elements Involved in the Transcriptional Initiation of RpoS-Dependent Borrelia burgdorferi Genes
- Identification of Borrelia burgdorferi Outer Surface Proteins
- EbfC (YbaB) Is a New Type of Bacterial Nucleoid-Associated Protein and a Global Regulator of Gene Expression in the Lyme Disease Spirochete
- Porins of Borrelia burgdorferi
- Bacteriophages of spirochetes.
- Structure and Function of the Borrelia burgdorferi Porins, P13 and P66
- Microbial evasion of innate immunity by utilization of soluble complement regulators
- Borrelia burgdorferi B31 Erp Proteins That Are Dominant Immunoblot Antigens of Animals Infected with Isolate B31 Are Recognized by Only a Subset of Human Lyme Disease Patient Sera
- Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide.
- Example of Real‐Time Quantitative Reverse Transcription–PCR (Q‐RT‐PCR) Analysis of Bacterial Gene Expression during Mammalian Infection: Borrelia burgdorferi in Mouse Tissues
- Homology throughout the multiple 32-kilobase circular plasmids present in Lyme disease spirochetes
- The role of CD14 in signaling mediated by outer membrane lipoproteins of Borrelia burgdorferi.
- Borrelia burgdorferi gene expression profiling with membrane-based arrays.
- Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection
- Identification of quantitative trait loci governing arthritis severity and humoral responses in the murine model of Lyme disease.
- Characterization of cp18, a naturally truncated member of the cp32 family of Borrelia burgdorferi plasmids
- PPAR-α activation reduced LPS-induced inflammation in alveolar epithelial cells
- Surface exposure and protease insensitivity of Borrelia burgdorferi Erp (OspEF-related) lipoproteins.
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