A systematic analysis of Tinman function reveals Eya and JAK-STAT signaling as essential regulators of muscle development.
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Summary
It is shown that the stat92E expression pathway is essential for somatic muscle development in Drosophila and for myotome morphogenesis in zebrafish, and a conserved requirement for JAK/STAT signaling is uncovered.
- Type
- article
- Published
- 2009-02-17
- Cited by
- 90
- References
- 43
- Access
- Open access
- OpenAlex
- https://openalex.org/W1968465765
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31090566
Keywords
Biology, Myogenesis, Cell biology, MEF2C, Genetics
References
- GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila.
- A key role of Pox meso in somatic myogenesis of Drosophila
- Jelly belly: a Drosophila LDL receptor repeat-containing signal required for mesoderm migration and differentiation.
- ladybird determines cell fate decisions during diversification of Drosophila somatic muscles.
- The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster.
- Apterous is a Drosophila LIM domain gene required for the development of a subset of embryonic muscles.
- tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila.
- ChIP-on-chip protocol for genome-wide analysis of transcription factor binding in Drosophila melanogaster embryos
- Functional Roles of STAT Family Proteins: Lessons from Knockout Mice
- Cloning and expression of Drosophila SOCS36E and its potential regulation by the JAK/STAT pathway.
- The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling
- D-six4 plays a key role in patterning cell identities deriving from the Drosophila mesoderm.
- Congenital heart disease caused by mutations in the transcription factor NKX2-5.
- Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis.
- Inhibition of zebrafish fgf8 pre‐mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown
- Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo
- Identification of a Stat gene that functions in Drosophila development.
- Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.
- Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila.
- GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo.
Cited by
- Conservation and divergence in developmental networks: a view from Drosophila myogenesis.
- Decoding heterogeneous big data in an integrative way
- Contrôle transcriptionnel de l'identité musculaire chez la drosophile : modules cis-régulateurs et gènes cibles directs de Collier
- Cellular and Molecular Mechanisms Driving Glial Engulfment of Degenerating Axons: A Dissertation
- Expression, function and regulation of the Him gene during Drosophila heart development
- Encoding anatomy: Developmental gene regulatory networks and morphogenesis
- Predicting enhancer regions and transcription factor binding sites in D. melanogaster
- Genome-Wide Mapping of Collier In Vivo Binding Sites Highlights Its Hierarchical Position in Different Transcription Regulatory Networks
- Identification of cis-regulatory modules encoding temporal dynamics during development
- Combinatorial binding predicts spatio-temporal cis-regulatory activity
- Fish proteome analysis: Model organisms and non‐sequenced species
- Glycolysis supports embryonic muscle growth by promoting myoblast fusion
- Genome-Wide Screens for In Vivo Tinman Binding Sites Identify Cardiac Enhancers with Diverse Functional Architectures
- Eyes Absent Tyrosine Phosphatase Activity Is Not Required for Drosophila Development or Survival
- JAK-STAT pathway in Drosophila morphogenesis
- The myogenic repressor gene Holes in muscles is a direct transcriptional target of Twist and Tinman in the Drosophila embryonic mesoderm
- Six Homeoproteins Directly Activate Myod Expression in the Gene Regulatory Networks That Control Early Myogenesis
- Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development
- Using Evolutionary Conserved Modules in Gene Networks as a Strategy to Leverage High Throughput Gene Expression Queries
- Machine learning classification of cell-specific cardiac enhancers uncovers developmental subnetworks regulating progenitor cell division and cell fate specification
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