Nature of cold-reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus.
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Summary
Sera from patients with systemic lupus erythematosus (SLE), as detected by microcytotoxicity and indirect immunofluorescence, were predominantly cold reactive and of the IgM class, and the functional significance of these antilymphocyte antibodies is discussed.
- Type
- article
- Published
- 1975-01-01
- Cited by
- 174
- References
- 32
- OpenAlex
- https://openalex.org/W1967811983
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13535061
Keywords
Antibody, Immunology, Lupus erythematosus, Medicine, Cytotoxic T cell
References
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- Antibodies specific for human T lymphocytes in cold agglutinin and lymphocytotoxic sera
- Antibodies against cell membrane constituents in systemic lupus erythematosus and related diseases. I. Cytotoxic effect of serum from patients with systemic lupus erythematosus (SLE) for allogeneic and for autologous lymphocytes.
- Therapeutic suggestion. An important part of hypnotic medication.
- Age-decrease of cells sensitive to an autoantibody-specific for thymocytes and thymus-dependent lymphocytes in NZB mice.
- Lymphocyte subpopulations in NZB mice: deficit of thymus-dependent lymphocytes.
- Effects of natural thymocytotoxic autoantibody of NZB mice and of specifically prepared antilymphocyte serum on the tissue distribution of 51 Cr-labeled lymphocytes.
- SEROLOGICAL CHARACTERIZATION OF NATURAL ANTIHUMAN LYMPHOCYTOTOXIC ANTIBODIES IN MAMMALIAN SERA
- Inhibition of mixed leukocyte culture responses by serum and gamma-globulin fractions from certain patients with connective tissue disorders.
- The glomerular permeability determined by dextran clearance using Sephadex gel filtration.
- Relative T-cell specificity of lymphocytotoxins from patients with systemic lupus erythematosus.
- Direct lysis of lymphocytes by complement in patients with systemic lupus erythematosus.
- Natural thymocytolytic autoantibodies in NZB and other strains of mice.
- CYTOTOXINS IN DISEASE: III. Antibodies Against Lymphocytes Produced By Vaccination
- Relationship of the clinical course of systemic lupus erythematosus to the presence of circulating lymphocytotoxic antibodies.
- Lymphocyte Cytotoxic Antibodies in Systemic Lupus Erythematosus
- Antibodies to membrane antigen(s) common to thymocytes and a subpopulation of lymphocytes in infectious-mononucleosis sera.
- Microdroplet Assay of Human Serum Cytotoxins
- Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies.
- Human lymphocyte-sheep erythrocyte rosette formation: some characteristics of the interaction.
Cited by
- Monocyte-reactive antibodies in patients with systemic lupus erythematosus.
- Impaired IL2 production by lymphocytes of patients with systemic lupus erythematosus.
- Infectious agents in Crohn's disease-fact or artefact?
- E-rosette formation in Graves' ophthalmopathy.
- Immunological aspects of Werner's syndrome: an analysis of 17 patients.
- Anti-lymphocyte autoantibodies in systemic lupus erythematosus.
- Suppressor-cell antibody in systemic lupus erythematosus. Possible mechanism for suppressor-cell dysfunction.
- Autoimmune cytotoxic granulocyte antibodies in normal persons and various diseases.
- Naturally Occurring IgM Anti-Leukocyte Autoantibodies (IgM-ALA) Inhibit T Cell Activation and Chemotaxis1
- Brain Synaptosomal Antibodies in Systemic Lupus Erythematosus
- Reflections on Henry G Kunkel as a mentor in clinical investigation
- Direct demonstration of the function of T cell subsets reactive with anti-T cell antibodies from SLE sera
- Differential sensitivity of functional subsets of T cells to the cytotoxicity of natural T-lymphocytotoxic autoantibody of systemic lupus erythematosus.
- Serologic studies in patients with systemic lupus erythematosus and central nervous system dysfunction.
- Subset specificity of lupus antilymphocyte antibodies studied by two-colour microfluorimetry.
- Antibodies to CD45 and other cell membrane antigens in systemic lupus erythematosus
- Studies of immune functions of patients with systemic lupus erythematosus: antibodies to desialized, rather than intact, T cells preferentially bind to and eliminate suppressor effector T cells.
- A taxia telangiectasia: an autoimmune disease associated with a cytotoxic antibody to brain and thymus.
- Antibody-mediated suppression of antibody-dependent cytotoxic effector cell function.
- Systemic lupus erythematosus—an autoimmune disease?
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