Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2
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Summary
The results indicate that miR-20a/106a has a key role in GSC invasion and may serve as targets for treatment of glioblastoma.
- Type
- article
- Published
- 2014-04-07
- Cited by
- 126
- References
- 61
- Access
- Open access
- OpenAlex
- https://openalex.org/W1967434897
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21895549
Keywords
Biology, microRNA, Glioma, Gene knockdown, Cancer research
References
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Cited by
- The Effects of Antisense miRNA-20a Alone or in Combination with Imatinib on K562 Cell Proliferation
- The Effects and Molecular Mechanisms of MiR-106a in Multidrug Resistance Reversal in Human Glioma U87/DDP and U251/G Cell Lines
- Can lateral ventricle contact predict the ontogeny and prognosis of glioblastoma?
- DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells
- Design of a miRNA sponge for the miR-17 miRNA family as a therapeutic strategy against vulvar carcinoma.
- microRNA-20a enhances the epithelial-to-mesenchymal transition of colorectal cancer cells by modulating matrix metalloproteinases.
- Extracellular Matrix Communication and Turnover in Cardiac Physiology and Pathology
- miR-663 Suppresses Oncogenic Function of CXCR4 in Glioblastoma
- Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer
- miR-20a mediates temozolomide-resistance in glioblastoma cells via negatively regulating LRIG1 expression.
- MicroRNA-27b inhibits Spry2 expression and promotes cell invasion in glioma U251 cells
- Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+ liver cancer initiating cells by suppressing negative regulators of β-catenin signaling
- miRNA-regulated delivery of lincRNA-p21 suppresses β-catenin signaling and tumorigenicity of colorectal cancer stem cells
- miR-124 suppresses the migration and invasion of glioma cells in vitro via Capn4.
- MicroRNA-663 inhibits the proliferation, migration and invasion of glioblastoma cells via targeting TGF-β1.
- miR‐4299 mediates the invasive properties and tumorigenicity of human follicular thyroid carcinoma by targeting ST6GALNAC4
- A five-miRNA signature with prognostic and predictive value for MGMT promoter-methylated glioblastoma patients
- MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes.
- New Concepts in Cancer Biomarkers: Circulating miRNAs in Liquid Biopsies
- MicroRNA-106a functions as an oncogene in human gastric cancer and contributes to proliferation and metastasis in vitro and in vivo
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