INDUCTION OF HYPORESPONSIVENESS TO FULLY ALLOGENEIC CARDIAC GRAFTS BY INTRATRACHEAL DELIVERY OF ALLOANTIGEN1

Keywords

CD80, Medicine, CD86, Transplantation, Splenocyte

References

• Antigen presenting cells integrate opposing signals from CD4+ and CD8+ regulatory T lymphocytes to arbitrate the outcomes of immune responses.Carlos Díaz-Bertrana — 1999
• CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment.Xin Xiao Zheng, Thomas G. Markees, Wayne W. Hancock — 1999
• Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.Víctor Pérez, Luk Van Parijs, Andre Biuckians — 1997
• Oral, but not intravenous, alloantigen prevents accelerated allograft rejection by selective intragraft Th2 cell activation.Wayne W. Hancock, Mohamed H. Sayegh, CHENG A. KWOK — 1993
• DOWN‐REGULATION OF THE IMMUNE RESPONSE TO HISTOCOMPATIBILITY ANTIGENS AND PREVENTION OF SENSITIZATION BY SKIN ALLOGRAFTS BY ORALLY ADMINISTERED ALLOANTIGEN1Mohamed H. Sayegh, Z. Jenny Zhang, Wayne W. Hancock — 1992
• CTLA-4 can function as a negative regulator of T cell activation.Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker — 1994
• Mucosal tolerance and suppression of collagen‐induced arthritis (CIA) induced by nasal inhalation of synthetic peptide 184‐198 of bovine type II collagen (CII) expressing a dominant T cell epitopeNorman A. Staines, N. Harper, Frank J. Ward — 1996
• CTLA-4 is required for the induction of high dose oral tolerance.Elena B. Samoilova — 1998
• Antigen-driven bystander suppression after oral administration of antigensAriel Miller, Ofer Lider, Howard L. Weiner — 1991
• CD28/B7 system of T cell costimulation.Deborah J. Lenschow, Theresa L. Walunas, Jeffrey A. Bluestone — 1996
• Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized miceGerard F. Hoyne, Robyn E. O’Hehir, David C. Wraith — 1993
• Prevention of renal allograft rejection in primates by blocking the B7/CD28 pathway.Miriam A. Ossevoort, Jan Ringers, Eva-Maria Kuhn — 1999
• Specific acceptance of cardiac allografts after treatment with antibodies to CD80 and CD86 in mice.Hisashi Bashuda, Ken‐ichiro Seino, Masafumi Kano — 1996
• Oral tolerance.Karen Smith, Alfred D. Eaton, L. M. FINLAYSON — 2000

Cited by

• Antigen-induced suppressor T cells from the skin point of view: suppressor T cells induced through epicutaneous immunization.Margaret S. Bynoe, Christophe Viret — 2005
• In vitro characterisation and expansion of human regulatory T cells for their in vivo application in the induction of tolerance in haematopoietic stem cell and solid organ transplantationMarco Romano — 2015
• Depletion of Alveolar Macrophages Abrogates Prolongation of Cardiac Allograft Survival Induced by Intratracheal Delivery of AlloantigenDaiki Iwami, Qi Zhang, Osamu Aramaki — 2010
• FK 506 abrogates induction of regulatory cells after intratracheal delivery of alloantigen.Shintaro Shibutani, Yoshinobu Akiyama, Nozomu Shirasugi — 2002
• Immunotherapeutic strategies employing RNA interference technology for the control of cancers.Chih‐Ping Mao, Chien‐Fu Hung, T.‐C. Wu — 2007
• Role of the CTLA4 pathway in hyporesponsiveness induced by intratracheal delivery of alloantigen1Nozomu Shirasugi, Yoshinobu Akiyama, Osamu Aramaki — 2003
• B7/CTLA4 pathway is essential for generating regulatory cells after intratracheal delivery of alloantigen in mice1Yoshinobu Akiyama, Nozomu Shirasugi, Norio Uchida — 2002
• Induction of indefinite survival of fully allogeneic cardiac grafts and generation of regulatory cells by intratracheal delivery of alloantigens under blockade of the CD40 pathwayNorio Uchida, Nozomu Shirasugi, Yoshinobu Akiyama — 2003
• CD25+ regulatory cells generated by intratracheal delivery of alloantigen.Yoshinobu Akiyama, Shintaro Shibutani, Kotaro Matsumoto — 2002
• Effects of Immunosuppressants on Induction of Regulatory Cells After Intratracheal Delivery of AlloantigenShintaro Shibutani, Fumihiko Inoue, Osamu Aramaki — 2005
• Interleukin-10 but not Transforming Growth Factor-&bgr; is Essential for Generation and Suppressor Function of Regulatory Cells Induced by Intratracheal Delivery of AlloantigenOsamu Aramaki, Fumihiko Inoue, Tadatoshi Takayama — 2005
• Pathways of major histocompatibility complex allorecognitionBehdad Afzali, Giovanna Lombardi, Robert I. Lechler — 2008
• Co-inhibitory molecules: Controlling the effectors or controlling the controllers?Govindarajan Thangavelu, Christa Smolarchuk, Colin C. Anderson — 2010
• Intratracheal delivery of a single major histocompatibility complex class I peptide induced prolonged survival of fully allogeneic cardiac grafts and generated regulatory cells.Yoshinobu Akiyama, Nozomu Shirasugi, Osamu Aramaki — 2002
• Induction of operational tolerance and generation of regulatory cells after intratracheal delivery of alloantigen combined with nondepleting anti-CD4 monoclonal antibodyOsamu Aramaki, Nozomu Shirasugi, Yoshinobu Akiyama — 2003
• Programmed death-1–programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigenOsamu Aramaki, Nozomu Shirasugi, Tadatoshi Takayama — 2004
• CD27/CD70, CD134/CD134 ligand, and CD30/CD153 pathways are independently essential for generation of regulatory cells after intratracheal delivery of alloantigenOsamu Aramaki, Nozomu Shirasugi, Yoshinobu Akiyama — 2003
• Prevention of Chronic Rejection in Murine Cardiac Allografts: A Comparison of Chimerism- and Nonchimerism-Inducing Costimulation Blockade-Based Tolerance Induction Regimens1Nozomu Shirasugi, Andrew Adams, Megan M. Durham — 2002
• Administration of donor splenocytes via the respiratory tract generates CD8α+ regulatory dendritic cells and induces hyporesponsiveness to fully allogeneic cardiac grafts.Daiki Iwami, Osamu Aramaki, Nobuo Shinohara — 2018
• Induction Regimens Costimulation Blockade-Based Tolerance Chimerism-and Nonchimerism-Inducing Cardiac Allografts : A Comparison of Prevention of Chronic Rejection in MurineC. Larsen, Cowan, Matthew A. Williams — 2002

Related papers

• Differential role of CD80 and CD86 on alveolar macrophages in the presentation of allergen to T lymphocytes in asthmaPiero Emilio Balbo, M. Silvestri, Giovanni A. Rossi — 2001
• Differential expression of the costimulatory molecules CD86, CD28, CD152 and PD-1 correlates with the host-parasite outcome in leprosy.Maria de Lourdes Palermo, Maria Ângela Bianconcini Trindade, Alberto José da Silva Duarte — 2012
• Influence of anti-allergic agents on in vivo expression of co-stimulatory molecules in normal mice.E Tryka, Kazuhito Asano, Junya Ito — 1999
• Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice.Angela Haczku, Katsuyuki Takeda, Imre Rédai — 1999
• Modulation of the function of dendritic cells in adolescents with chronic HBV infection by IFN-λ1.Hai‐hua Sun, Lijuan Bi, Junying Zhou — 2015
• [Effects of Bushen Jiedu Recipe and Jianpi Jiedu Recipe containing plasma on dendritic cells of chronic hepatitis B virus infection patients under different immune states].Song Ou, Ke-wei Sun, Jianping Peng — 2013
• The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA MiceVasiliy V. Kurilin, Julia N. Khantakova, Valeriy P. Tereschenko — 2019