Self-stimulation responses are altered following long-term but not short-term treatment with clorgyline.
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Summary
Findings suggest that adaptative alterations in the modulation of rewarded behavior by inhibitory presynaptic noradrenergic receptors may be involved in antidepressant efficacy.
- Type
- article
- Published
- 1983-07-04
- Cited by
- 23
- References
- 16
- OpenAlex
- https://openalex.org/W1967121205
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28456234
Keywords
Clorgyline, Stimulation, Antidepressant, Agonist, Monoamine oxidase
References
- Monoamine oxidase in sympathetic nerves: a transmitter specific enzyme type
- alpha-Adrenergic modulation of hypothalamic self-stimulation: effects of phenoxybenzamine, yohimbine, dexamphetamine and their interactions with clonidine.
- alpha 2-adrenoceptor-mediated hyperpolarization of locus coeruleus neurons: intracellular studies in vivo.
- Effects of chronic desipramine treatment on rat brain noradrenergic responses to alpha-adrenergic drugs.
- Feedback inhibition of brain noradrenaline neurons by tricyclic antidepressants: alpha-receptor mediation.
- Evidence for a central noradrenaline receptor stimulation by clonidine.
- Presynaptic alpha-adenoceptors: the depression of self-stimulation by clonidine and its restoration by piperoxane but not by phentolamine or phenoxybenzamine.
- Functional evidence for subsensitivity of noradrenergic alpha 2 receptors after chronic desipramine treatment.
- Repeated electroconvulsive shock attenuates clonidine-induced hypoactivity in rodents.
- Increased intracranial self-stimulation in rats after long-term administration of desipramine.
- Interaction of antidepressants with clonidine on rat brain total 3-methoxy-4-hydroxyphenylglycol.
- Comparative Trial of a New Mono-Amine Oxidase Inhibitor in Depression
- The central basis of motivation: intracranial self-stimulation studies.
- Antidepressants and alpha 2-adrenergic autoreceptor desensitization.
- The effect of antidepressant drugs and cocaine on the self-stimulation in rats.
Cited by
- Selective amine oxidase inhibitors: basic to clinical studies and back.
- How antidepressants work: cautionary conclusions based on clinical and laboratory studies of the longer-term consequences of antidepressant drug treatment.
- Different effects of short- and long-term treatment with imipramine on the apomorphine- and food-induced place preference conditioning in rats.
- Therapeutic responses to tricyclic antidepressants and related drugs in non-affective disorder patient populations.
- A behavioural and neurochemical analysis of chronic and selective monoamine oxidase inhibition
- Antidepressants in states of cognitive dysfunction
- Studies on the Role of α2‐Adrenoceptors in the Control of Synaptosomal [3H]5‐Hydroxytryptamine Release: Effects of Antidepressant Drugs
- Long-term desipramine treatment attenuates clonidine-induced suppression of ventral tegmental self-stimulation.
- The interaction of thyroid state, MAOI drug treatment, and light on the level and circadian pattern of wheel-running in rats.
- Clorgyline and desipramine alter the sensitivity of [3H]noradrenaline release to calcium but not to clonidine.
- Electrophysiological and receptor studies in rat brain: effects of clorgyline.
- Acute and chronic desipramine treatment effects on rewarding electrical stimulation of the lateral hypothalamus.
- Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
- Clorgyline treatment differentially affects m-chlorophenylpiperazine-induced neuroendocrine changes.
- Effects of chronically administered antidepressant drugs on animal behavior.
- Action of antidepressants on the septal nuclei of the rat.
- Chronic treatment with antidepressant drugs and ECT differentially modifies the hypothermic action of clonidine and guanfacine.
- Fenfluramine-induced suppression of food intake and locomotor activity is differentially altered by the selective type A monoamine oxidase inhibitor clorgyline
- Electrical intra-cranial self-stimulation: a potentially valid model for antidepressant action
- Recent Developments Regarding the Use of Monoamine Oxidase Inhibitors in Psychopharmacology
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