Citric acid cycle (TCA cycle)

Summary

The biochemical details of this reaction have been worked out with alpha ketoglutarate dehydrogenase complex and subunits purified from bovine tissue and unpublished crystallographic data indicate that the protein is a tetramer.

Keywords

Citric acid cycle, Citric acid, Chemistry, Biochemistry, Metabolism

References

Biosynthesis of tricarboxylic acids by carbon dioxide fixation; enzymatic mechanisms.Severo Ochoa — 1948
The oxidation of pyruvate in pigeon breast muscle.H. A. Krebs, L. V. Eggleston — 1940
Di- and triphosphopyridine nucleotide isocitric dehydrogenases in yeast.Arthur Kornberg, W.E. Pricer — 1951
The formation of citric and alpha-ketoglutaric acids in the mammalian body.H. A. Krebs, Ernest Salvin, William A. Johnson — 1938
Structure-function relationships in dihydrolipoamide acyltransferases.Lester J. Reed, Marvin L. Hackert — 1990
Mitochondrial energy-linked nicotinamide nucleotide transhydrogenase. Membrane topography of the bovine enzyme.Mutsuo Yamaguchi, Youssef Hatefi — 1991
STUDIES ON SUCCINATE DEHYDROGENASE. I. SPECTRAL PROPERTIES OF THE PURIFIED ENZYME AND FORMATION OF ENZYME-COMPETITIVE INHIBITOR COMPLEXES.D.V. Dervartanian, C. Veeger — 1964
Human NAD(+)-dependent mitochondrial malic enzyme. cDNA cloning, primary structure, and expression in Escherichia coli.G Loeber, Anthony A. Infante, Ingrid Maurer-Fogy — 1991
Purification, cDNA cloning and heterologous expression of the human mitochondrial NADP(+)-dependent malic enzyme.G Loeber, Ingrid Maurer-Fogy, R Schwendenwein — 1994
Guanosine triphosphate, the primary product of phosphorylation coupled to the breakdown of succinyl coenzyme A.D.R. Sanadi, D. M. Gibson, Padmasini Ayengar — 1954
Mutation of the fumarase gene in two siblings with progressive encephalopathy and fumarase deficiency.Thomas Bourgeron, Dominique Chrétien, Jo Poggi-Bach — 1994
Interaction between succinyl CoA synthetase and the heme-biosynthetic enzyme ALAS-E is disrupted in sideroblastic anemia.Kazumichi Furuyama, Shigeru Sassa — 2000
Genetic Evidence for the Expression of ATP- and GTP-specific Succinyl-CoA Synthetases in Multicellular Eucaryotes*James D. Johnson, James G. Mehus, K Tews — 1998
Expression of Two Succinyl-CoA Synthetases with Different Nucleotide Specificities in Mammalian Tissues*David O. Lambeth, K Tews, Steven Adkins — 2004
Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase.Sambanthamurthy Soundar, Jung‐Hoon Park, Tae‐Lin Huh — 2003
Characterization of the ATP- and GTP-specific Succinyl-CoA Synthetases in PigeonJames D. Johnson, Wallace W. Muhonen, David O. Lambeth — 1998
Crystal Structure of Porcine Mitochondrial NADP+-dependent Isocitrate Dehydrogenase Complexed with Mn2+ and IsocitrateC. Ceccarelli, Neil B. Grodsky, Nandana Ariyaratne — 2002
X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880Babu A. Manjasetty, F. Niesen, Heinrich Delbrück — 2004
The pursuit of a hobby.Severo Ochoa — 1980
Structure and function of malic enzymes, a new class of oxidative decarboxylases.Gu‐Gang Chang, Liang Tong — 2003

Cited by

The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myelomaKanagaraju Ponnusamy, Maria‐Myrsini Tzioni, M. S. T. Monira Begum — 2020

Related papers

ФОРМИРОВAНИЕ ГОТОВНОСТИ БУДУЩИХ ПЕДAГОГОВ К ОРГAНИЗAЦИИ РAБОТЫ ПО РAЗВИТИЮ ВAЛЕОЛОГИЧЕСКОЙ КУЛЬТУРЫ ШКОЛЬНИКОВАльбина Мингалиевна Базарбаева, Ш.М. МАЙГЕЛЬДИЕВА, Т.Н. ЖҮНДІБАЕВА — 2023
DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATIONNor Hanim Mustafa, Dinmukhamed Kelesbayev, Zh.D. Alibekova — 2018
A GEOMETRIC MEAN IN THE FURUTA INEQUALITYMasatoshi Fujii, Ritsuo Nakamoto — 2002
PHOTOMETRISCHE JODIDBESTIMMUNG NEBEN UEBERSCHUESSIGEN CHLORIDEN UND BROMIDENJ. Novák, I. Sláma — 1972
KORROSION VON ZINK IN LOESUNGEN VON AMMONIUMCHLORID UND WEITEREN CHLORIDENL. A. SHOPEN, I.P. Anoshchenko — 1973
Chemistry of Pyridazines. Part 36. Novel Diaza-Analogues of 10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-one.W. Dostal, Gottfried Heinisch, G. LOETSCH — 1989
CHEMISTRY OF PLEUROMUTILINS. VII. BASE-INDUCED TRANSANNULAR 1,4-HYDRIDE SHIFT IN 8-SUBSTITUTED PLEUROMUTILIN DERIVATIVESHeinz Berner, Hermann Vyplel, G. Schulz — 1983