Management of severe acute to fulminant hepatitis B: to treat or not to treat or when to treat?
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Summary
In severe acute HBV with prolonged prothrombin time and increased bilirubin, interferon failed to be effective while antiviral treatment, particularly with lamivudine, appears to improve survival (mean survival almost 80%).
- Type
- review
- Published
- 2012-04-01
- Cited by
- 59
- References
- 115
- OpenAlex
- https://openalex.org/W1966159761
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24379018
Keywords
Medicine, Fulminant, Fulminant hepatitis, Intensive care medicine, Acute hepatitis
References
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- Lamivudine treatment is associated with improved survival in fulminant hepatitis B
- Late onset of hepatitis B virus reactivation following hematopoietic stem cell transplantation: successful treatment with combined entecavir plus tenofovir therapy
- Hepatitis B re‐activation with rituximab therapy: treat the patient not the disease
Cited by
- Shifting hepatitis B virus genotypes of acute hepatitis B patients in northeast Japan
- Tenofovir versus Entecavir in Treatment of Chronic Hepatitis B Virus with Severe Acute Exacerbation
- Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice
- Recommendations for the management of acute hepatitis B: position paper of the Italian Society for the Study of Infectious and Tropical Diseases (SIMIT)
- Fulminant viral hepatitis.
- Chronic hepatitis B in 2014: great therapeutic progress, large diagnostic deficit.
- Hepatitis crónica por virus B. Historia natural y tratamiento
- Severe acute hepatitis B in a treatment‐naïve patient with antiviral drug resistant mutations in the polymerase gene
- Endothelial Nitric Oxide Synthase (eNOS) Gene Polymorphism is Associated with Age Onset of Menarche in Sickle Cell Disease Females of India
- Hepatitis B virus seropositivity among schistosomiasis and diabetes mellitus patients in Sana'a City, Yemen.
- Successful treatment of Acute Fulminant Liver Failure due to Hepatitis B virus with Entecavir in patients with contra-indications to liver transplant
- Entecavir Versus Lamivudine Therapy for Patients With Chronic Hepatitis B-Associated Liver Failure: A Meta-Analysis
- Treatment of severe, nonfulminant acute hepatitis B with lamivudine vs placebo: a prospective randomized double‐blinded multicentre trial
- Tenofovir as Rescue Therapy Following Clinical Failure to Lamivudine in Severe Acute Hepatitis B
- Micro RNAs mir‐106a, mir‐122 and mir‐197 are increased in severe acute viral hepatitis with coagulopathy
- Acute liver failure caused by severe acute hepatitis B: a case series from a multi-center investigation
- The efficacy and safety of entecavir in patients with chronic hepatitis B- associated liver failure: a meta-analysis.
- An economic evaluation of contingency management for completion of hepatitis B vaccination in those on treatment for opiate dependence
- To Treat or Not to Treat? : A Case of Severe Acute Hepatitis-B Treated with Entecavir Compared to a Case of Milder, Untreated Disease
- Management of Chronic Hepatitis in Special Hosts and Special Situations: A Consensus Report of the Study Group for Viral Hepatitis of the Turkish Society of Clinical Microbiology and Infectious Diseases
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