Remodelling the extracellular matrix in development and disease
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Summary
The extracellular matrix is crucial for regulating the morphogenesis of the intestine and lungs, as well as of the mammary and submandibular glands, and its regulation contributes to several pathological conditions, such as fibrosis and invasive cancer.
- Type
- review
- Published
- 2014-11-21
- Cited by
- 3,913
- References
- 170
- Access
- Open access
- OpenAlex
- https://openalex.org/W1965498876
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12711748
Keywords
Extracellular matrix, Morphogenesis, Matrix metalloproteinase, Cell biology, Fibrosis
References
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- A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms*
- Exploring mechanisms of FGF signalling through the lens of structural biology
- Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis
- Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
- Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
- Extracellular matrix: not just pretty fibrils
- Expression of matrix metalloproteinase genes in regressing or remodeling organs during amphibian metamorphosis
- Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing
- A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis
- A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation12
- The regulation of the ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review.
- Proteases and small intestinal barrier function in health and disease
- Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4.
- ECM-modulated cellular dynamics as a driving force for tissue morphogenesis
- The role of extracellular matrix in CNS regeneration.
- Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
- The matrix metalloproteinase stromelysin-3 cleaves laminin receptor at two distinct sites between the transmembrane domain and laminin binding sequence within the extracellular domain
- Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesis
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- Extracellular matrix dynamics and functions in the social amoeba Dictyostelium: A critical review.
- Cancer metastasis: Mechanisms of inhibition by melatonin
- Reorganized Collagen in the Tumor Microenvironment of Gastric Cancer and Its Association with Prognosis
- Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1
- Implantation of Brain-Derived Extracellular Matrix Enhances Neurological Recovery after Traumatic Brain Injury
- Supplemental psyllium fibre regulates the intestinal barrier and inflammation in normal and colitic mice
- SWATH mass spectrometry as a tool for quantitative profiling of the matrisome
- ADAMTS9-Regulated Pericellular Matrix Dynamics Governs Focal Adhesion-Dependent Smooth Muscle Differentiation
- LRP1 is required for novobiocin-mediated fibronectin turnover
- The VP1 unique region of human parvovirus B19 and human bocavirus induce lung injury in naïve Balb/c mice
- Deep Tumor‐Penetrated Nanocages Improve Accessibility to Cancer Stem Cells for Photothermal‐Chemotherapy of Breast Cancer Metastasis
- Reciprocal intra- and extra-cellular polarity enables deep mechanosensing through layered matrices
- Fibronectin extra domain a limits liver dysfunction and protects mice during acute inflammation
- The Construction of Three-Layered Biomimetic Arterial Graft Balances Biomechanics and Biocompatibility for Dynamic Biological Reconstruction
- Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing
- The Extracellular Matrix: Tools and Insights for the “Omics” Era
- Interactions of Hepatitis B Virus Infection with Nonalcoholic Fatty Liver Disease: Possible Mechanisms and Clinical Impact
- Reduction of plasma fibulin-1 predicts poor survival in metastatic colorectal cancer
- Metabolism and successful aging: Polymorphic variation of syndecan-4 (SDC4) gene associate with longevity and lipid profile in healthy elderly Italian subjects.
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