In vitro and in vivo interactions between nuclear receptors at estrogen response elements.
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Summary
This model could be used to identify mammalian factors interacting with estrogen and retinoic acid receptors which could play a role in crosstalk between these receptors.
- Type
- article
- Published
- 1996-08-01
- Cited by
- 5
- References
- 34
- OpenAlex
- https://openalex.org/W1965411293
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34830902
Keywords
Estrogen receptor, Retinoic acid, Retinoid X receptor, Receptor, PELP-1
References
- Interaction between retinoic acid and vitamin D signaling pathways.
- Ligand-specific transactivation of gene expression by a derivative of the human glucocorticoid receptor expressed in yeast.
- Interplay between estrogens, progestins, retinoic acid and AP-1 on a single regulatory site in the progesterone receptor gene.
- Powerful dominant negative mutants of the human estrogen receptor.
- Differential ligand‐dependent interactions between the AF‐2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.
- Specificity and flexibility of vitamin D signaling. Modulation of the activation of natural vitamin D response elements by thyroid hormone.
- Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.
- Antiestrogenic effects of all-trans-retinoic acid and 1,25-dihydroxyvitamin D3 in breast cancer cells occur at the estrogen response element level but through different molecular mechanisms.
- Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors.
- Retinoic acid acts synergistically with 1,25-dihydroxyvitamin D3 or antioestrogen to inhibit T-47D human breast cancer cell proliferation.
- Functional analysis of the human estrogen receptor using a phenotypic transactivation assay in yeast.
- Homo- and heterodimers of the retinoid X receptor (RXR) activated transcription in yeast.
- Study of an antiestrogenic effect of retinoic acid in MCF-7 cells.
- The human oestrogen receptor functions in yeast
- The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements.
- Gene regulation by steroid hormones.
- Yeast: an experimental organism for modern biology.
- 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor.
- Interaction of thyroid-hormone receptor with a conserved transcriptional mediator
- Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling.
Cited by
- RIP 140 enhances nuclear receptor-dependent transcription in vivo in yeast.
- Increases in mouse uterine heat shock protein levels are a sensitive and specific response to uterotrophic agents.
- Melatonin inhibits mitogenic cross-talk between retinoic acid-related orphan receptor alpha (RORalpha) and ERalpha in MCF-7 human breast cancer cells.
- A Genomic Mechanism for Antagonism Between Retinoic Acid and Estrogen Signaling in Breast Cancer
- Efficacy of LGD1069 (Targretin), a retinoid X receptor-selective ligand, for treatment of uterine leiomyoma.
- RIP 140 Enhances Nuclear Receptor-Dependent Transcription in Vivo in Yeast
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- Table of Contents
- Retinoic Acid Receptor/Retinoid X Receptor Heterodimers Can Be Activated through Both Subunits Providing a Basis for Synergistic Transactivation and Cellular Differentiation*
- The nuclear receptor corepressor (N-CoR) modulates basal and activated transcription of genes controlled by retinoic acid.
- Two distinct actions of retinoid-receptor ligands
- Is 9-cis-retinoic acid the endogenous ligand for the retinoic acid-X receptor?