Expression of a transfected human c-myconcogene inhibits differentiation of a mouse erythroleukaemia cell line
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Summary
Experiments reported here indicate that expression in MEL cells of a transf ected human c-myc gene inhibits the terminal differentiation process.
- Type
- article
- Published
- 1986-08-21
- Cited by
- 271
- References
- 17
- OpenAlex
- https://openalex.org/W1965137961
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4250807
Keywords
Transfection, Cell culture, Cellular differentiation, Biology, Cell cycle
References
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- A new technique for the assay of infectivity of human adenovirus 5 DNA.
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- Versatile cosmid vectors for the isolation, expression, and rescue of gene sequences: studies with the human alpha-globin gene cluster.
- c-myc mRNA levels in the cell cycle change in mouse erythroleukemia cells following inducer treatment.
- Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia
- Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.
- Detection of specific sequences among DNA fragments separated by gel electrophoresis.
- Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation.
- The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma.
- Murine myb protooncogene mRNA: cDNA sequence and evidence for 5' heterogeneity.
- Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.
- Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis.
Cited by
- Myc family of cellular oncogenes
- Probability that the commitment of murine erythroleukemia cell differentiation is determined by the c-myc level.
- Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia.
- Expression and function of the c-myb oncogene during hematopoietic differentiation.
- c-Myc in the control of cell proliferation and embryonic development.
- Regulated expression and function of the c-Myc antagonist, Mad1, during a molecular switch from proliferation to differentiation.
- Growth factors in human germ cell cancer.
- Tiazofurin induction of mouse erythroleukemia cell hemoglobin production in the absence of commitment or changes in protooncogene expression.
- Evaluation by multivariate analysis of the differentiation inhibitory factor nm23 as a prognostic factor in acute myelogenous leukemia and application to other hematologic malignancies.
- Amplified expression of three jun family members inhibits erythroleukemia differentiation.
- Control of c-myc regulation in normal and neoplastic cells.
- The myc family of nuclear proto-oncogenes.
- Interaction of oncogenes with differentiation programs.
- Molecular genetic analysis of lymphoid tumors arising after organ transplantation.
- Myeloblastic leukemia cells conditionally blocked by myc-estrogen receptor chimeric transgenes for terminal differentiation coupled to growth arrest and apoptosis.
- Dioctanoylglycerol and phorbol esters regulate transcription of c-myc in human promyelocytic leukemia cells.
- Proteins of the Myc network: essential regulators of cell growth and differentiation.
- raf/myc-infected erythroid cells are restricted in their ability to terminally differentiate
- Functions of myc:max in the control of cell proliferation and tumorigenesis.
- MYC and MNT in transcriptional regulation and chromatin dynamics
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