Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury.
Explore this paper's citation graph
Summary
A soluble form of human KIM-1 can be detected in the urine of patients with ATN and may serve as a useful biomarker for renal proximal tubule injury facilitating the early diagnosis of the disease and serving as a diagnostic discriminator.
- Type
- article
- Published
- 2002-07-01
- Cited by
- 1,905
- References
- 26
- Access
- Open access
- OpenAlex
- https://openalex.org/W1964405385
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36996213
Keywords
Medicine, Acute kidney injury, Acute tubular necrosis, Kidney, Urinary system
References
- Urinary biomarkers: recommendations of the Joint European/United States Workshop for future research.
- Noninvasive renal diagnostic studies.
- Biomedical testing of the kidney for persons exposed to hazardous substances in the environment.
- Urinary excretion of brush-border antigen revealed by monoclonal antibody: early indicator of toxic nephropathy.
- Regeneration after acute tubular necrosis.
- Cell biology and molecular mechanisms of injury in ischemic acute renal failure.
- Quantitating the severity of proximal tubular brush border injury by a simple direct binding radioimmunoassay.
- Determinants of survival and recovery in acute renal failure patients dialyzed in intensive-care units.
- Biocompatible membranes in acute renal failure: prospective case-controlled study.
- Gamma-glutamyltransferase is a reliable marker for tubular effects of contrast media.
- Biocompatible membranes in acute renal failure: prospective case-controlled study.
- Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule Containing a Novel Immunoglobulin Domain, Is Up-regulated in Renal Cells after Injury*
- Hospital-acquired renal insufficiency: a prospective study.
- Detection of the early steps of cadmium nephropathy--comparison of light- and electron-microscopical patterns with the urinary enzymes excretion. An experimental study.
- Urinary excretion rates of multiple renal indicators after kidney transplantation: clinical significance for early graft outcome.
- Expression of 90-kDa heat shock protein within regenerative tubular cells in a patient with acute oliguric renal failure due to malignant hypertension.
- Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.
- High risk acute renal failure.
- Choice of Time for Urine Collection for Detecting Early Kidney Abnormalities in Hypertensives
- Circadian rhythm of glomerular filtration rate in normal individuals.
Cited by
- Urinary biomarkers for the detection of renal injury.
- Acute renal failure definitions and classification: time for change?
- Prediction of Nephrotoxicant Action and Identification of Candidate Toxicity-Related Biomarkers
- Early diagnosis of acute kidney injury
- Biomarkers of acute kidney injury in children: discovery, evaluation, and clinical application
- Myocardial infarction impairs renal function, induces renal interstitial fibrosis, and increases renal KIM-1 expression: implications for cardiorenal syndrome.
- Diabetic nephropathy: traditional to proteomic markers.
- Urine proteomics in kidney transplantation.
- Efficacy of Gold Nanoparticles against Nephrotoxicity Induced by Schistosoma mansoni Infection in Mice.
- Novel Biomarkers of Heart Failure.
- Serelaxin improves cardiac and renal function in DOCA-salt hypertensive rats
- Identification of Diagnostic Urinary Biomarkers for Acute Kidney Injury
- Biomarkers of acute kidney injury in anesthesia, intensive care and major surgery: from the bench to clinical research to clinical practice.
- New markers of acute kidney injury: giant leaps and baby steps.
- The Role of KIM-1 Mediated Efferocytosis by Cancer Cells in Blocking the Immunogenicity of Tumor Cell Death
- Insuffisance rénale aiguë : intérêt des nouveaux biomarqueurs
- Investigation of biomarkers of hepatic and renal toxicity in the Han Wistar rat
- Kidney-specific proteins: markers for detection of renal dysfunction after cardiac surgery?
- TIM gene family and their role in atopic diseases.
- Proteomics and systems biology: application in drug discovery and development.
Related papers
- DEVELOPMENT OF CHRONIC KIDNEY DISEASE AFTER ACUTE KIDNEY INJURY IN PATIENTS WITH CIRRHOSIS IS COMMON AND IMPAIRS CLINICAL OUTCOMES.
- A Case of Severe Acute Kidney Injury by Near-Drowning
- РАСПРОСТРАНЕННОСТЬ, ФАКТОРЫ РИСКА И ИСХОДЫ ОСТРОГО ПОВРЕЖДЕНИЯ ПОЧЕК В РАННЕМ ПОСЛЕОПЕРАЦИОННОМ ПЕРИОДЕ У ПАЦИЕНТОВ С ХРОНИЧЕСКОЙ БОЛЕЗНЬЮ ПОЧЕК ПОСЛЕ КОРОНАРНОГО ШУНТИРОВАНИЯ
- Urinary biomarkers for acute kidney injury: perspectives on translation.
- Recovery from acute renal failure after 11 months of hemodialysis.
- Recovery from acute renal failure after 11 months of hemodialysis