On regulation of phagosome maturation and antigen presentation
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Summary
The presence of a subcellular level of self–non-self discrimination in dendritic cells that operates at the level of individual phagosomes is highlighted and engagement of Toll-like receptor signaling controls distinct programs of phagosome maturation is discussed.
- Type
- review
- Published
- 2006-10-01
- Cited by
- 319
- References
- 70
- Access
- Open access
- OpenAlex
- https://openalex.org/W1964168671
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:863982
Keywords
Phagosome, Phagocytosis, Cell biology, Antigen presentation, Biology
References
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- Pathogen recognition and innate immunity.
- A Critical Role for Syk in Signal Transduction and Phagocytosis Mediated by Fcγ Receptors on Macrophages
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- Molecular motors hijacking by intracellular pathogens
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- Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
- Phagocytosis and clearance of apoptotic cells is mediated by MER
- Monocyte and macrophage heterogeneity
Cited by
- Initial receptor-ligand interactions modulate gene expression and phagosomal properties during both early and late stages of phagocytosis.
- The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity
- Dendritic cell-based immunotherapy in myeloid leukaemia: translating fundamental mechanisms into clinical applications.
- Induction of Apoptosis and Subsequent Phagocytosis of Virus-Infected Cells As an Antiviral Mechanism
- Mechanisms by Which Dendritic Cells Present Tumor Microparticle Antigens to CD8+ T Cells
- The kinetics and distribution of different macrophage populations in the developing rat skin.
- The role of Axl/Mertk/Tyro3 receptor tyrosine kinases in the clearance of apoptotic cells
- CD14 Modulates PI3K/AKT/p38-MAPK Licensing of Negative Regulators of TLR Signaling to Restrain Chronic Inflammation
- Myeloperoxidase is associated with cognitive function, brain morphology and subjective well-being in a cohort of elderly marathon runners
- Long-term Effects of Severe Sepsis on Dendritic Cell Function.
- Toll-like Receptor Signaling and its Effects on Microbial Pathogenesis
- Quantitating MHC class II trafficking in primary dendritic cells using imaging flow cytometry
- TOLL-LIKE RECEPTOR 2 EXPRESSION, REGULATION AND SIGNALING
- Role of the redox responsive transcription factor, NRF2, in immune cell function
- Immunphänotypische Analyse autoreaktiver T-Zellen nach endogener Reaktivierung der EAE in der SJL-Maus
- Metalloproteinase Expression in Bone Marrow-derived Macrophages: Roles in Cell Migration
- IgG-mediated Immune Suppression: the Effect on the Host Immune System
- HMGB1, RAGE, and the Myeloid Response to Pancreatic Cancer
- Roles of dendritic cells in immunity to Toxoplasma gondii
- Towards programming immune tolerance through geometric manipulation of phosphatidylserine
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