Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.
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Summary
Ghrelin probably functions not only in the control of GH secretion, but also in the regulation of diverse processes of the digestive system, and its findings provide clues to additional physiological functions of this novel gastrointestinal hormone.
- Type
- article
- Published
- 2000-11-01
- Cited by
- 1,925
- References
- 12
- Access
- Open access
- OpenAlex
- https://openalex.org/W1964081706
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:207073317
Keywords
Ghrelin, Enteroendocrine cell, Internal medicine, Endocrinology, Enterochromaffin cell
References
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- Ultrastructural localization of antigenic sites on osmium-fixed tissues applying the protein A-gold technique.
- Physiology of isolated gastric endocrine cells.
- Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.
- [Chromogranins in endocrine cells of the digestive system].
- Enterochromaffin-Like Cells, a Cellular Source of Uroguanylin in Rat Stomach*
- Enterochromaffin-Like Cells, a Cellular Source of Uroguanylin in Rat Stomach
- Printed in U.S.A. Copyright © 1999 by The Endocrine Society Enterochromaffin-Like Cells, a Cellular Source of Uroguanylin in Rat Stomach*
Cited by
- Human ghrelin modifies lipid metabolism of the common frog Rana temporaria
- Ghrelin-a new gastroprotective factor in gastric mucosa.
- Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium
- Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach.
- Ghrelin, Leptin and Insulin Levels after Restrictive Surgery: a 2-Year Follow-up Study
- Effects of gastric emptying on the postprandial ghrelin response.
- Plasma leptin and ghrelin concentrations in patients with Crohn's disease.
- Histamine Mediates the Stimulatory Action of Ghrelin on Acid Secretion in Rat Stomach
- Review: long-term impact of bariatric surgery on body weight, comorbidities, and nutritional status.
- Prokinetic Effects of a New Ghrelin Receptor Agonist TZP-101 in a Rat Model of Postoperative Ileus
- Effects of pinealectomy and exogenous melatonin on ghrelin and peptide YY in gastrointestinal system and neuropeptide Y in hypothalamic arcuate nucleus: immunohistochemical studies in male rats.
- Ghrelin—a novel generation of anti‐obesity drug: design, pharmacomodulation and biological activity of ghrelin analogues
- Ghrelin cell density in the gastrointestinal tracts of animal models of human diabetes.
- Ghrelin immunoexpression in pituitary adenomas
- Standard sample collections for blood ghrelin measurements.
- Expression of Serum Retinol Binding Protein and Transthyretin within Mouse Gastric Ghrelin Cells
- Impairment of ghrelin synthesis in Helicobacter pylori-colonized stomach: new clues for the pathogenesis of H. pylori-related gastric inflammation.
- Diet in irritable bowel syndrome
- The effects of auricular acupuncture on weight reduction and feeding-related cytokines: a pilot study
- Assessments of plasma ghrelin levels in the early stages of parkinson's disease
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