Variable receptors controlling activation and inhibition of NK cells.
Explore this paper's citation graph
Summary
Once considered relatively homogeneous, NK cells are now seen to be highly diverse, and expression of different combinations of inhibitory and stimulatory receptors creates a diverse NK cell repertoire, which exhibits specificity in the immune response.
- Type
- review
- Published
- 2002-10-01
- Cited by
- 209
- References
- 103
- OpenAlex
- https://openalex.org/W1963962536
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43433662
Keywords
Biology, Receptor, Effector, Immune receptor, Cell biology
References
- Cutting Edge: Induction of IFN-γ Production but Not Cytotoxicity by the Killer Cell Ig-Like Receptor KIR2DL4 (CD158d) in Resting NK Cells
- Natural killer and leucocyte receptor complexes
- On guard—activating NK cell receptors
- Localization on a physical map of the NKC-linked Cmv1 locus between Ly49b and the Prp gene cluster on mouse chromosome 6.
- Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor.
- Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice.
- Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
- Positive recognition of MHC class I molecules by the Ly49D receptor of murine NK cells.
- Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages
- Allelic Polymorphism Synergizes with Variable Gene Content to Individualize Human KIR Genotype1
- KIR2DL5, a Novel Killer-Cell Receptor with a D0-D2 Configuration of Ig-Like Domains1 2
- Different NK Cell Surface Phenotypes Defined by the DX9 Antibody Are Due to KIR3DL1 Gene Polymorphism1
- SHP-1- and Phosphotyrosine-Independent Inhibitory Signaling by a Killer Cell Ig-Like Receptor Cytoplasmic Domain in Human NK Cells1
- Diversity of NK cell receptor repertoire in adult and neonatal mice.
- Conservation and Variation in Human and Common Chimpanzee CD94 and NKG2 Genes1
- Direct Recognition of Cytomegalovirus by Activating and Inhibitory NK Cell Receptors
- Selective expression of NKG2-A and NKG2-C mRNAs and novel alternative splicing of 5′ exons in rhesus monkey decidua
- The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene cluster
- Identification of the rat homologue of the human NKp46 triggering receptor.
- Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3.
Cited by
- Thomsen‐Friedenreich (T) antigen expression increases sensitivity of natural killer cell lysis of cancer cells
- The role of leukocytes bearing Natural Killer Complex receptors and Killer Immunoglobulin-like Receptors in the immunology of malaria.
- Flow cytometry in detection of abnormalities of natural killer cell.
- Functional analysis of MICA polymorphism : with an emphasis on Behcet's disease
- Mechanisms of virally vectored immunocontraception
- Natural Cytotoxicity of NC‐2+ Cells Against the Growth and Metastasis of WEHI‐164 Fibrosarcoma
- MHC class I antigens and immune surveillance in transformed cells.
- Donor NK cell licensing in control of malignancy in hematopoietic stem cell transplant recipients
- ORIGINAL ARTICLE: A High Dose of Intravenous Immunoglobulin Increases CD94 Expression on Natural Killer Cells in Women with Recurrent Spontaneous Abortion
- Activation of natural killer cells by hepatitis C virus particles in vitro
- The KIR Gene Cluster
- Increased Susceptibility to Apoptosis of CD56dimCD16+ NK Cells Induces the Enrichment of IFN-γ-Producing CD56bright Cells in Tuberculous Pleurisy1
- Interactions between NK cells and B lymphocytes.
- Stimulatory Killer Ig-Like Receptors Modulate T Cell Activation through DAP12-Dependent and DAP12-Independent Mechanisms1
- Independent Control of Ly49g Alleles: Implications for NK Cell Repertoire Selection and Tumor Cell Killing1
- The effect of human cytomegalovirus on innate immune responses : Immune activation and evasion
- Molekularbiologische und funktionelle Charakterisierung neuer "Chicken Ig-like" Rezeptoren
- Ly49 genes in non-rodent mammals
- Immune evasion of Human Cytomegalovirus : Studies of UL18 and US2 function
- The zebrafish as a model organism to study development of the immune system.
Related papers
- Cross-reactivity of a rice NLR immune receptor to distinct effectors from the blast pathogen leads to partial disease resistance
- Cross-reactivity of a rice NLR immune receptor to distinct effectors from the rice blast pathogen Magnaporthe oryzae provides partial disease resistance
- The Major Histocompatibility Complex of Old World Camels—A Synopsis
- Innate immune receptors in type 1 diabetes: the relationship to cell death-associated inflammation.
- Mechanisms of MHC class I‐restricted antigen processing and cross‐presentation
- Neurons Preferentially Respond to Self-MHC Class I Allele Products Regardless of Peptide Presented
- Human Herpesvirus 7 U21 Tetramerizes To Associate with Class I Major Histocompatibility Complex Molecules
- NetMHCpan, a method for MHC class I binding prediction beyond humans