IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

Keywords

Calphostin C, Proinflammatory cytokine, Protein kinase A, Calphostin, Protein kinase C

References

• Prostaglandin E2 inhibits the release of tumor necrosis factor-alpha, rather than interleukin 1 beta, from human macrophages.Gyula Huszenicza, Orsolya Balogh, László Fésüs — 1992
• Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor.Lawrence E. Samelson, Richard D. Klausner — 1992
• IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells.Pengtao Wang, Ping Wu, Marvín I. Siegel — 1994
• Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosine monophosphate.Peter Juel Thiis Knudsen, C A Dinarello, T B Strom — 1986
• Ca2+ and calmodulin selectively regulate lipopolysaccharide-inducible cytokine mRNA expression in murine peritoneal macrophages.Yoshihiro Ohmori, Thomas A. Hamilton — 1992
• Adherence induces selective mRNA expression of monocyte mediators and proto-oncogenes.Stephen Haskill, C.W Johnson, David Eierman — 1988
• Transcriptional activation of IL-1 beta and tumor necrosis factor-alpha genes by MHC class II ligands.Nikolaus S. Trede, R S Geha, Talal A. Chatila — 1991
• IL-2. A cofactor for induction of activated macrophage resistance to infection.Miodrag Belosevic, D S Finbloom, Monte S. Meltzer — 1990
• Regulation of activated macrophage antimicrobial activities. Identification of lymphokines that cooperate with IFN-gamma for induction of resistance to infection.Miodrag Belosevic, Charles E. Davis, Monte S. Meltzer — 1988
• The oxidative metabolism of thioglycollate-elicited mouse peritoneal macrophages: the relationship between oxygen, superoxide and hydrogen peroxide and the effect of monolayer formation.M S Cohen, John L. Ryan, RK Root — 1981
• Human IL-17: a novel cytokine derived from T cells.Zemin Yao, Sally Painter, William C. Fanslow — 1995
• Intracellular localization of human monocyte associated interleukin 1 (IL 1) activity and release of biologically active IL 1 from monocytes by trypsin and plasmin.Koji Matsushima, M. Taguchi, Éva Kovács — 1986
• IL-10 inhibits the synthesis of migration inhibitory factor and migration inhibitory factor-mediated macrophage activation.Jiayi Wu, Fernando Q. Cunha, F Y Liew — 1993
• Effects of granulocyte-macrophage colony-stimulating factor and colony-stimulating factor-1 on the proliferation and differentiation of murine alveolar macrophages.Kiyoko S. Akagawa, Keiichi Kamoshita, T Tokunaga — 1988
• Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-alpha and IL-1 beta production by human monocytes.Lior Shapira, Shogo Takashiba, Catherine M. Champagne — 1994
• Enhanced production of LPS-induced cytokines during differentiation of human monocytes to macrophages. Role of LPS receptors.Sandra Gessani, Ugo Testa, Barbara Varano — 1993
• Human monocyte adherence: a primary effect of chemotactic factors on the monocyte to stimulate adherence to human endothelium.Dennis E. Doherty, Chris Haslett, Marcia G. Tonnesen — 1987
• Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa BMartine A. Collart, Patrick A. Baeuerle, P Vassalli — 1990
• Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide.Robert C. Fuhlbrigge, David Chaplin, Jeanne-Marie Kíely — 1987
• Cyclic AMP signaling pathways are important in IL-1 beta transcriptional regulation.Gyan Chandra, John Cogswell, Larry R. Miller — 1995

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