Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

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Summary

The results suggested that the unusual capacity of MERS-CoV to infect T cells and induce apoptosis might partly contribute to the high pathogenicity of the virus.

Type
article
Published
2015-07-22
Cited by
418
References
51
Access
Open access

Keywords

Biology, Spleen, Apoptosis, Middle East respiratory syndrome coronavirus, Pathogenesis

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