Cellular and molecular mechanisms of hepatic fibrogenesis leading to liver cancer
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Summary
It is often overlooked that 90% of HCC cases have a natural history of unresolved inflammation and severe fibrosis (or cirrhosis), and approaches to HCC prevention should focus on the molecular regulators of a disease process that could define as the inflammation-fibrosis-cancer (IFC) axis.
- Type
- article
- Published
- 2011-12-30
- Cited by
- 22
- References
- 71
- OpenAlex
- https://openalex.org/W1945277476
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:70762522
Keywords
Hepatocellular carcinoma, Medicine, Cirrhosis, Fibrosis, Liver cancer
References
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- Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog
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- Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis
Cited by
- Supplementation of fresh ucche (Momordica charantia L. var. muricata Willd) prevented oxidative stress, fibrosis and hepatic damage in CCl4 treated rats
- Evaluation of seven different staging systems for alpha-fetoprotein expression in hepatocellular carcinoma after hepatectomy
- Oxidative stress as a crucial factor in liver diseases.
- Comparison of lipid profile in different grades of non-alcoholic fatty liver disease diagnosed on ultrasound
- FERM family proteins and their importance in cellular movements and wound healing (review).
- The potential of silymarin for the treatment of hepatic disorders
- Elevated serum &agr;-fetoprotein levels in patients with chronic hepatitis C virus genotype 4: not the end of the story
- TGF-β–independent CTGF induction regulates cell adhesion mediated drug resistance by increasing collagen I in HCC
- An investigation of the role of glucose and fructose in non-alcoholic fatty liver disease using systems approaches
- Lipid profile in different grades of Ultrasonic Non-Alcoholic Fatty Liver Disease
- Drugs and Targets in Fibrosis
- Data Mining and Machine Learning Algorithms Using IL28B Genotype and Biochemical Markers Best Predicted Advanced Liver Fibrosis in Chronic Hepatitis C.
- Crocin potentiates antioxidant defense system and improves oxidative damage in liver tissue in diabetic rats.
- Study of Lipid Profile in Different grades of Non- Alcoholic Fatty Liver Disease
- Correlation Between TGF-β1 and c-MET Expression in HCV Genotype 4-Induced Liver Fibrosis
- Liver stiffness measurement changes following hepatocellular carcinoma treatment with percutaneous microwave ablation or transarterial chemoembolization: a cohort study
- Dendropanax morbifera Ameliorates Thioacetamide-Induced Hepatic Fibrosis via TGF-β1/Smads Pathways
- Dually Efficacious Medicine Against Fibrosis and Cancer
- Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/C Mice
- Data mining machine learning algorithms using IL 28 B genotype and biochemical markers best predicted advanced liver fibrosis in chronic HCV Running title : Data mining predicting HCV advanced fibrosis
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