Kinetics of Analgesic Response in Man; an Example with Two Non-Steroidal Anti-Inflammatory Analgesic Drugs
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Summary
A double-blind, controlled clinical trial is described in which hospital in-patients suffering from severe post-operative pain were randomly allocated to treatment with one of two non-steroidal anti-inflammatory drugs, namely, either indoprofen or naproxen.
- Type
- article
- Published
- 1978-07-01
- Cited by
- 12
- References
- 17
- OpenAlex
- https://openalex.org/W1945201730
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27141733
Keywords
Analgesic, Medicine, Pharmacology, Analgesic agents, Anesthesia
References
- Application of Nonparametric Procedure for Bioassay Data to the Evaluation of Analgesics in Man
- Fundamentals of Clinical Pharmacokinetics
- Naproxen oral absorption characteristics.
- Pharmacokinetics of drug action.
- Absorption, distribution, metabolism, and excretion of naproxen in various laboratory animals and human subjects.
- Naproxen Metabolism in Man
- Influence of age on pain relief from analgesics. A study of postoperative patients.
- Kinetics of pharmacologic effects in man: The anticoagulant action of warfarin
- Statistical Tables: For Biological, Agricultural and Medical Research
- Indoprofen, a new analgesic and anti‐inflammatory drug in cancer pain
- Pharmacokinetic studies of indoprofen in healthy volunteers and in patients.
- Effect of food on absorption of indoprofen administered orally to man in two dosage forms.
- Relationship of pentazocine plasma levels to pharmacological activity in man
Cited by
- Relief of pain and trismus in patients treated with naproxen or acetylsalicylic acid after tonsillectomy
- Single dose oral naproxen and naproxen sodium for acute postoperative pain (Review)
- Single dose oral naproxen and naproxen sodium for acute postoperative pain in adults.
- Indoprofen, a new non-steroidal anti-inflammatory drug, in the treatment of osteoarthrosis: report on a multi-centre study in 1629 patients.
- Effect of moxifloxacin administration on pharmacokinetics of tolfenamic acid in rats
- Naproxen up to Date: A Review of its Pharmacological Properties and Therapeutic Efficacy and Use in Rheumatic Diseases and Pain States
- Pharmacokinetics and pharmacodynamics of tolfenamic acid in calves.
- The Analgesic Effect of Intravenous Indoprofen and Lysine Acetylsalicylate in Patients with Postoperative Pain 1
- The Protective Effect of Field Mint Leaves in Reducing Stomach Ulcer in Rats Induced by Aspirin
- Pharmacokinetic factors as causes of variability in response to non-steroidal anti-inflammatory drugs.
- Ibuprofen Arginine vs Naproxen Sodium as Prophylactic Oral Treatment of Pain Due to Dental Surgery
- Selected bibliography
- Indoprofen: A Review of Human Studies
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