Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.
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Summary
Results reveal that CTL mainly exert perforin-based cytotoxicity and complementary Fas- based cytotoxic activity, and that CMA is a powerful tool to clarify the contributions of the two distinct cytolytic pathways.
- Type
- article
- Published
- 1996-05-15
- Cited by
- 457
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1943839210
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22161310
Keywords
Perforin, CTL*, Cytolysis, Cytotoxicity, Cytotoxic T cell
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