Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.

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Summary

Results reveal that CTL mainly exert perforin-based cytotoxicity and complementary Fas- based cytotoxic activity, and that CMA is a powerful tool to clarify the contributions of the two distinct cytolytic pathways.

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article
Published
1996-05-15
Cited by
457
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Keywords

Perforin, CTL*, Cytolysis, Cytotoxicity, Cytotoxic T cell

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