MicroRNA-124 reduces the pentose phosphate pathway and proliferation by targeting PRPS1 and RPIA mRNAs in human colorectal cancer cells.

Keywords

microRNA, Gene knockdown, Cancer research, Cell growth, Cell culture

References

• miR-574-5p negatively regulates Qki6/7 to impact β-catenin/Wnt signalling and the development of colorectal cancerMolly Farrell — 2012
• MiR-124 targets Slug to regulate epithelial–mesenchymal transition and metastasis of breast cancerPaul Piwek — 2012
• Cancer treatment and survivorship statistics, 2016Сергей Юрьевич Просветов — 2016
• MicroRNA-218 Inhibits Cell Cycle Progression and Promotes Apoptosis in Colon Cancer by Downregulating BMI1 Polycomb Ring Finger OncogeneXinqi He, Yujuan Dong, Chung Wah Wu — 2012
• MicroRNA-130b promotes tumor development and is associated with poor prognosis in colorectal cancer.Tommaso Colangelo, Alessandra Fucci, Carolina Votino — 2013
• MicroRNA‐30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2Wenting Liao, Y. Ye, Nian‐Jie Zhang — 2014
• miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect.Yan Sun, Xiaoping Zhao, Yuhong Zhou — 2012
• Glucose transporters in cancer metabolismKehinde Adekola, Steven T. Rosen, Mala Shanmugam — 2012
• Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?László G. Boros, P.W.N. Lee, J.L. Brandes — 1998
• Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growthChangliang Shan, Shannon Elf, Quanjiang Ji — 2014
• Proteomic Analysis of Colorectal Cancer Reveals Alterations in Metabolic PathwaysXuezhi Bi, Qingsong Lin, Tet Wei John Foo — 2006
• MicroRNA-124 Regulates STAT3 Expression and is Downregulated in Colon Tissues of Pediatric Patients with Ulcerative ColitisΓεώργιος Κούκος, Christos Polytarchou, Jess L. Kaplan — 2013
• Tumor cell metabolism: cancer's Achilles' heel.Guido Kroemer, Jacques Pouysségur — 2008
• Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosisAtsushi Hamabe, Hirofumi Yamamoto, Masamitsu Konno — 2014
• MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cellsLea H. Gregersen, Anders J. Skanderup, Lisa B. Frankel — 2012
• The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.Ralph J. DeBerardinis, Julian J. Lum, Georgia Hatzivassiliou — 2008
• Cancer cell metabolism: Warburg and beyond.Peggy P. Hsu, David M. Sabatini — 2008
• The Pro-Apoptotic Role of the Regulatory Feedback Loop between miR-124 and PKM1/HNF4α in Colorectal Cancer CellsYan Sun, Xiaoping Zhao, Man Luo — 2014
• Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cellsX-B Shi, Lingru Xue, A-H Ma — 2012
• MiR-124 Suppresses Growth of Human Colorectal Cancer by Inhibiting STAT3Jufeng Zhang, Yanxin Lu, Xupeng Yue — 2013

Cited by

• Targeting metabolic reprogramming associated to cancer cells: search of novel targets and combined therapies in cancer treatmentMíriam Neus Tarrado Castellarnau — 2015
• Ribose 5-phosphate isomerase inhibits LC3 processing and basal autophagyJacob Heintze, Joana R. Costa, M. Weber — 2016
• Phosphoribosylpyrophosphate Synthetase 1 Knockdown Suppresses Tumor Formation of Glioma CD133+ Cells Through Upregulating Cell ApoptosisChen Li, Zhongjie Yan, Xu‐Hua Cao — 2016
• Oncogenic regulation of tumor metabolic reprogrammingMíriam Tarrado‐Castellarnau, Pedro de Atauri, Marta Cascante — 2016
• Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseasesWuhong Pei, Lisha Xu, Gaurav K. Varshney — 2016
• MiR-608, pre-miR-124-1 and pre-miR26a-1 polymorphisms modify susceptibility and recurrence-free survival in surgically resected CRC individualsHou‐Qun Ying, Hong-Xin Peng, Bangshun He — 2016
• PRPS1 silencing reverses cisplatin resistance in human breast cancer cells.Min He, Lin Chao, Yi-Ping You — 2017
• RETRACTED: Downregulation of FBP1 Promotes Tumor Metastasis and Indicates Poor Prognosis in Gastric Cancer via Regulating Epithelial-Mesenchymal TransitionJing Li, Ying Wang, Qingguo Li — 2016
• miR-150 inhibits proliferation and tumorigenicity via retarding G1/S phase transition in nasopharyngeal carcinomaXiangyong Li, Fumei Liu, Bihua Lin — 2017
• Post-Transcriptional and Post-translational Regulation of Central Carbon Metabolic Enzymes in Cancer.Yunqian Wang, Yingxuan Chen, Jing‐Yuan Fang — 2017
• Pioglitazone-mediated reversal of elevated glucose metabolism in the airway epithelium of mouse lung adenocarcinomas.Donghai Xiong, Jing Pan, Qi Zhang — 2017
• MicroRNA-552 promotes tumor cell proliferation and migration by directly targeting DACH1 via the Wnt/β-catenin signaling pathway in colorectal cancer.Jia Cao, Xiurui Yan, Ting Liu — 2017
• The role of ribose-5-phosphate isomerase A in the regulation of autophagyJ. Heintze — 2016
• Identification of Cancer–associated Metabolic Vulnerabilities by Modeling Multi-objective Optimality in MetabolismZiwei Dai, Li‐Yan Xu, Hongrong Hu — 2017
• Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domainYu‐Ting Chou, Jeng‐Kai Jiang, Muh‐Hwa Yang — 2018
• Prognostic value of microRNAs in colorectal cancer: a meta-analysisSong Gao, Zhiying Zhao, Rong Wu — 2018
• MicroRNA-129-5p Regulates Glycolysis and Cell Proliferation by Targeting the Glucose Transporter SLC2A3 in Gastric Cancer CellsDi Chen, Hui Wang, Jie Chen — 2018
• A miR-124/ITGA3 axis contributes to colorectal cancer metastasis by regulating anoikis susceptibility.Ke-di Sa, Xiang Zhang, Xiaofei Li — 2018
• Metabolic recoding of epigenetics in cancerYi‐Ping Wang, Qun‐Ying Lei — 2018
• Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer CellsMaria M. Szwarc, Ramakrishna Kommagani, Vasanta Putluri — 2018

Related papers

• RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafishRevathi Raman, Mia Ryon, Pudur Jagadeeswaran — 2020
• Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathwayHai Hu, Yanan Wang, Yan Dong — 2023
• Knockdown of ecdysteroid synthesis genes results in impaired molting and high mortality in Bactericera cockerelli (Hemiptera: Triozidae).Jorge R. Paredes‐Montero, Usman Arif, Judith K. Brown — 2022
• Supplementary Revised Figure S3 from MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53Imayavaramban Lakshmanan, Shereen Salfity, Parthasarathy Seshacharyulu — 2023
• Supplementary Revised Figure S3 from MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53Imayavaramban Lakshmanan, Shereen Salfity, Parthasarathy Seshacharyulu — 2023
• Embryo-to-embryo variability in RNAi knockdown efficiency of dKDM5/lid in Drosophila melanogasterAshley Albright, Michael B. Eisen — 2021
• Knockdown of HuR represses osteosarcoma cells migration, invasion and stemness through inhibition of YAP activation and increases susceptibility to chemotherapeutic agents.Wei Xu, Chao Chen, Ruijun Xu — 2018
• siRNA-mediated knockdown of the Nav1.8 sodium channelSameer P. Goregaoker, Todd Machemer, Murali Ramachandra — 2005
• Intramyocardial Injection of siRNAs Can Efficiently Establish Myocardial Tissue-Specific Renalase Knockdown Mouse ModelKun Huang, Ju Liu, Hui Zhang — 2016
• Study on the expression of IGF-IR on human gastric cancer cells inhibited by special small interfering RNADing Juan-juan — 2008