SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.

Keywords

SOD1, Amyotrophic lateral sclerosis, Excitotoxicity, Neurotoxicity, Mutation

References

• ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study.友則 大野 — 2007
• Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregationThomas H. Patten, Lester E. Dorey — 2008
• A role for motoneuron subtype–selective ER stress in disease manifestations of FALS miceТатьяна Ивановна Багаева — 2009
• Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanismsLeslie I. Grad, Justin J. Yerbury, Bradley J. Turner — 2014
• Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosisMarco Milanese, Simona Zappettini, Franco Onofri — 2011
• An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non–cell autonomous neurodegenerationGilbert Gallardo, Jessica Barowski, John Ravits — 2014
• Familial amyotrophic lateral sclerosisArnulf Eestnes, Svein Ivar Mellgren — 1980
• TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral SclerosisJemeen Sreedharan, Ian P. Blair, Vineeta B. Tripathi — 2008
• Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn‐superoxide dismutase mutant miceMaria Damiano, Anatoly A. Starkov, Susanne Petri — 2006
• Wild‐type superoxide dismutase acquires binding and toxic properties of ALS‐linked mutant forms through oxidationSamer Abou Ezzi, Makoto Urushitani, Jean‐Pierre Julien — 2007
• Deficits in axonal transport precede ALS symptoms in vivoLynsey G. Bilsland, Erik Sahai, Gavin Kelly — 2010
• Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis.Jeffrey D. Rothstein, Lee J. Martin, Ralph W. Kuncl — 1992
• Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.Masao Watanabe, Margaret Dykes‐Hoberg, Valeria Culotta — 2001
• Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral SclerosisRobert J. Ferrante, Susan Browne, Leslie A. Shinobu — 1997
• Toxic mutants in Charcot's sclerosisDon W. Cleveland, Nigel G. Laing, P.V. Hurse — 1995
• Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells.Fumito Endo, Okiru Komine, Noriko Fujimori-Tonou — 2015
• Experimental transmissibility of mutant SOD1 motor neuron diseaseJacob I. Ayers, Susan Fromholt, Morgan Koch — 2014
• GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.Ke Li, Tamara J. Hala, Suneil Seetharam — 2015
• Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits and early mortality in transgenic miceYa-Fei Xu, Tania F. Gendron, Yong‐Jie Zhang — 2010
• Exposure of Hydrophobic Surfaces Initiates Aggregation of Diverse ALS-Causing Superoxide Dismutase-1 MutantsChristian Münch, Anne Bertolotti — 2010

Cited by

• Redox Imbalance and Viral Infections in Neurodegenerative DiseasesDolores Limongi, Sara Baldelli — 2016
• Endogenous Cu in the central nervous system fails to satiate the elevated requirement for Cu in a mutant SOD1 mouse model of ALS.James B. Hilton, Anthony R. White, Peter J. Crouch — 2016
• Reactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic PlasticityThiago Fernando Beckhauser, José Fernando de Oliveira, Roberto De Pasquale — 2016
• Management and therapeutic perspectives in amyotrophic lateral sclerosisStéphane Mathis, Philippe Couratier, Adrien Julian — 2017
• Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicityChunxing Yang, Eric Danielson, Tao Qiao — 2016
• Intrinsic disorder in proteins involved in amyotrophic lateral sclerosisNikolas Santamaria, Marwa Alhothali, Maria Belen Harreguy Alfonso — 2017
• The Identification and Targeting of Partially-Folded Conformations on the Folding Free-Energy Landscapes of ALS-Linked Proteins for Therapeutic Intervention: A DissertationB. Mackness — 2016
• A Boronic Acid Conjugate of Angiogenin that Shows ROS-Responsive Neuroprotective ActivityTrish T. Hoang, Thomas P. Smith, Ronald T. Raines — 2017
• Evaluating a Gene-Environment Interaction in Amyotrophic Lateral Sclerosis: Methylmercury Exposure and Mutated SOD1Jordan Bailey, Alexandra Colón-Rodríguez, William D. Atchison — 2017
• Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleusYongwang Zhong, Jiou Wang, Mark J. Henderson — 2017
• Determining Protein-Protein Interactions of ALS-Associated SOD1Leah A. Shurte — 2016
• Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.James A. McCubrey, Kvin Lertpiriyapong, Linda S. Steelman — 2017
• The regulatory and signaling mechanisms of the ASK family.T. Nishida, Kazuki Hattori, Kengo Watanabe — 2017
• Implications of white matter damage in amyotrophic lateral sclerosisTing Zhou, Tina Khorshid Ahmad, Kiana Gozda — 2017
• TDP-43 and FUS in Amyotrophic Lateral Sclerosis: From Animal Models to Disease MechanismsSarah Y. Ebstein — 2017
• ASK1 in neurodegeneration.Xiaoli Guo, Kazuhiko Namekata, Atsuko Kimura — 2017
• NLRP3 Inflammasome Activation in a Transgenic Amyotrophic Lateral Sclerosis ModelAgnese Gugliandolo, Sabrina Giacoppo, Placido Bramanti — 2018
• Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals.James A. McCubrey, Stephen L. Abrams, Kvin Lertpiriyapong — 2017
• The roles of intrinsic disorder-based liquid-liquid phase transitions in the “Dr. Jekyll–Mr. Hyde” behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degenerationVladimir N. Uversky — 2017
• Therapeutic application of apoptosis signal-regulating kinase 1 inhibitors.Takao Fujisawa — 2017

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