The D2 Dopamine Receptor Gene as a Determinant of Reward Deficiency Syndrome
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Summary
It is proposed that variants of the D2 dopamine receptor gene are important common genetic determinants of the ‘reward deficiency syndrome’.
- Type
- review
- Published
- 1996-07-01
- Cited by
- 466
- References
- 66
- Access
- Open access
- OpenAlex
- https://openalex.org/W1920680810
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2304452
Keywords
Dopaminergic, Dopamine receptor D2, Dopamine, Dopamine receptor, Tourette syndrome
References
- Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism.
- The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.
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- Alcoholism and alleles of the human D2 dopamine receptor locus. Studies of association and linkage.
- D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5‐hydroxyindoleacetic acid and 3‐methoxy‐4‐hydroxyphenylglycol in alcoholics in Finland and the United States
- Prolonged P300 latency in children with the D2 dopamine receptor A1 allele.
- Lack of association between an RFLP near the D2 dopamine receptor gene and severe alcoholism.
- No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism.
- Hyperactive boys almost grown up. IV. Criminality and its relationship to psychiatric status.
- Dopamine D2 receptor RFLPs, haplotypes and their association with substance use in black and Caucasian research volunteers.
- Genetic vulnerability to drug abuse. The D2 dopamine receptor Taq I B1 restriction fragment length polymorphism appears more frequently in polysubstance abusers.
- Linkage disequilibria at the D2 dopamine receptor locus (DRD2) in alcoholics and controls.
- Dopamine D2 receptor gene variants: association and linkage studies in impulsive-addictive-compulsive behaviour.
- Subtypes of dopamine receptors involved in the mechanism of reinforcement.
- Effects of the dopamine‐related drug bromocriptine on event‐related potentials and its relation to the law of initial value
- Association between severity of alcoholism and the A1 allele of the dopamine D2 receptor gene TaqI A RFLP in Japanese.
- Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism.
- The D2 dopamine receptor gene: A review of association studies in alcoholism
- Substance abuse vulnerability and D2 receptor genes
Cited by
- Neurobiological correlates of problem gambling in a quasi-realistic blackjack scenario as revealed by fMRI.
- A Targeted Review of the Neurobiology and Genetics of Behavioral Addictions: An Emerging Area of Research
- Bitter taste function-related genes are implicated in the behavioral association between taste preference and ethanol preference in male mice.
- Pharmacogenetics of the G protein-coupled receptors.
- G protein-coupled receptor pharmacogenetics.
- Motion and Emotion : Functional In Vivo Analyses of the Mouse Basal Ganglia
- Genetic Factors in the Regulation of Striatal and Extrastriatal Dopamine D2 Receptor Expression
- Neural Circuit Analyses of the Olfactory System in Drosophila: Input to Output: A Dissertation
- A case of pathological gambling--its features and mangement.
- Nur-related receptor 1 gene polymorphisms and alcohol dependence in Mexican Americans.
- Treatment development in problem and pathological gambling
- New approach to the neurobiological mechanisms of addiction.
- GENETIC ADDICTION RISK SCORE (GARS) ANALYSIS: EXPLORATORY DEVELOPMENT OF POLYMORPHIC RISK ALLELES IN POLY-DRUG ADDICTED MALES
- Lonely reflections: Variations in adolescents' trait and state loneliness
- Interactions among attention-deficit hyperactivity disorder (ADHD) and problem gambling in a probabilistic reward-learning task.
- Addiction : entries and exits
- Psychophysiological responses to wins, losses, and losses disguised as wins during gambling on electronic machines: from laboratory tasks to live gambling
- Psychological theories of hyperactivity:a behaviour genetic approach
- The neurobiology of reward processing in adolescence
- The psychosocial impact of online problem gambling
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