Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data.

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Summary

Application of AMOVA to human mitochondrial DNA haplotype data shows that population subdivisions are better resolved when some measure of molecular differences among haplotypes is introduced into the analysis, and Monte Carlo studies show that site sampling does not fundamentally affect the significance of the molecular variance components.

Type
article
Published
1992-05-30
Cited by
14,430
References
51
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Open access

Keywords

Biology, Analysis of molecular variance, Haplotype, Population, Genetics

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