Mutational dissection of the S/T‐kinase StkP reveals crucial roles in cell division of Streptococcus pneumoniae
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Summary
It is concluded that StkP is a multifunctional protein that plays crucial functions in pneumococcus cell shape and division and specifically phosphorylates in vivo the cell division protein DivIVA on threonine 201.
- Type
- article
- Published
- 2012-02-01
- Cited by
- 108
- References
- 48
- Access
- Open access
- OpenAlex
- https://openalex.org/W1914172730
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205370715
Keywords
Biology, Cell division, Peptidoglycan, Cell biology, Kinase
References
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- A Eukaryotic-like Ser/Thr Kinase Signals Bacteria to Exit Dormancy in Response to Peptidoglycan Fragments
- Crystal Structure of PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate
- Control of cell morphogenesis in bacteria: two distinct ways to make a rod-shaped cell.
- Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes.
- Streptococcus pneumoniae DivIVA: Localization and Interactions in a MinCD-Free Context
- Identification of Multiple Substrates of the StkP Ser/Thr Protein Kinase in Streptococcus pneumoniae
- Phosphoproteomic analysis reveals the multiple roles of phosphorylation in pathogenic bacterium Streptococcus pneumoniae.
- An rpsL Cassette, Janus, for Gene Replacement through Negative Selection in Streptococcus pneumoniae
- The Extracytoplasmic Domain of the Mycobacterium tuberculosis Ser/Thr Kinase PknB Binds Specific Muropeptides and Is Required for PknB Localization
- The different shapes of cocci.
- Diverse paths to midcell: assembly of the bacterial cell division machinery.
- pETPhos: a customized expression vector designed for further characterization of Ser/Thr/Tyr protein kinases and their substrates.
- Two-Component Signaling Circuit Structure and Properties
- Post-translational modifications in signal integration
- The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
- Identification and biochemical characterization of a eukaryotic-type serine/threonine kinase and its cognate phosphatase in Streptococcus pyogenes: their biological functions and substrate identification.
- Expression and maintenance of ComD–ComE, the two‐component signal‐transduction system that controls competence of Streptococcus pneumoniae
Cited by
- Studies on polar cell wall growth and antibiotic susceptibility of Corynebacterium glutamicum
- Nucleotide‐independent cytoskeletal scaffolds in bacteria
- The Cell Wall of Streptococcus pneumoniae
- Interaction of Penicillin‐Binding Protein 2x and Ser/Thr protein kinase StkP, two key players in Streptococcus pneumoniae R6 morphogenesis
- Pbp2x Localizes Separately from Pbp2b and Other Peptidoglycan Synthesis Proteins during Later Stages of Cell Division of Streptococcus pneumoniae D39
- Regulation of apical growth and hyphal branching in Streptomyces.
- Ser/Thr phosphorylation as a regulatory mechanism in bacteria
- MapZ beacons the division sites and positions FtsZ-rings in Streptococcus pneumoniae
- The PASTA domain of penicillin-binding protein SpoVD is dispensable for endospore cortex peptidoglycan assembly in Bacillus subtilis.
- Protein-tyrosine phosphorylation interaction network in Bacillus subtilis reveals new substrates, kinase activators and kinase cross-talk
- Interplay of the Serine/Threonine-Kinase StkP and the Paralogs DivIVA and GpsB in Pneumococcal Cell Elongation and Division
- LocZ Is a New Cell Division Protein Involved in Proper Septum Placement in Streptococcus pneumoniae
- Gluconate 5-dehydrogenase (Ga5DH) participates in Streptococcus suis cell division
- Protein-serine/threonine/tyrosine kinases in bacterial signaling and regulation.
- Regulation of competence for natural transformation in streptococci.
- Protein Kinase A (PknA) of Mycobacterium tuberculosis Is Independently Activated and Is Critical for Growth in Vitro and Survival of the Pathogen in the Host*
- Interaction sites of DivIVA and RodA from Corynebacterium glutamicum
- Establishment and regulation of polar growth in Streptomyces
- Phosphorylation of the cell division protein GpsB regulates PrkC kinase activity through a negative feedback loop in Bacillus subtilis
- Protein-Protein Interaction Domains of Bacillus subtilis DivIVA
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