Deletions fusing the hisG and hisD genes in Salmonella typhimurium
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Summary
It is proposed that a combined inactive G-D polypeptide is synthesized and then cleaved at a number of closely juxtaposed sites by endoproteolytic activity, and at least some of the resulting fragments then participate in formation of active HDH dimers.
- Type
- article
- Published
- 1975-09-01
- Cited by
- 10
- References
- 45
- Access
- Open access
- OpenAlex
- https://openalex.org/W1913413974
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12694803
Keywords
Biology, Frameshift mutation, Gene, Salmonella, Genetics
References
- Classification and mapping of spontaneous and induced mutations in the histidine operon of Salmonella.
- Histidinol Dehydrogenase (hisD) Mutants of Salmonella typhimurium
- Purification and composition studies of phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase, the first enzyme of histidine biosynthesis.
- Translation and polarity in the histidine operon. 3. The isolation of prototrophic polar mutations.
- Analysis of amino acid phenylthiohydantoins by gas chromatography.
- Effects of protease inhibitors on protein breakdown in Escherichia coli.
- Histidine regulatory mutants in Salmonella typhimurium. IV. A positive selection for polar histidine-requiring mutants from histidine operator constitutive mutants.
- Composition and subunit structure of histidinol dehydrogenase from Salmonella typhimurium.
- Derivation of an F-Merogenote and a φ80 High-Frequency Transducing Phage Carrying the Histidine Operon of Salmonella
- Proteolytic release of a histidinol dehydrogenase fragment from the double enzyme histidinol dehydrogenase-imidazolylacetol-phosphate: L-glutamate aminotransferase.
- Histidinol dehydrogenase from Salmonella typhimurium. Crystallization and composition studies.
- Multiple aggregation states of phosphoribosyladenosine triphosphate synthetase.
- his-Linked Hydrogen Sulfide Locus in Salmonella typhimurium
- Some improved methods in P22 transduction.
- Nature of the hisD3018 Frameshift Mutation in Salmonella typhimurium
- Evidence for Proteolytic Degradation of Histidinol Phosphate Phosphatase Specified by Nonsense Mutants of the hisB Gene of Salmonella typhimurium
- Mutation leading to gene fusion in the histidine operon of Salmonella typhimurium.
- Relative translation frequencies of the cistrons of the histidine operon.
- Polypeptide cleavages in the formation of poliovirus proteins.
- Thin-layer chromatography of PTH amino acids
Cited by
- Purification and in vitro complementation of mutant histidinol dehydrogenases
- A refined map of the hisG gene of Salmonella typhimurium.
- Four-base codons ACCA, ACCU and ACCC are recognized by frameshift suppressor sufJ.
- Tandem chromosomal duplications in Salmonella typhimurium: fusion of histidine genes to novel promoters.
- The influence of codon context on genetic code translation
- Primary and secondary structural homologies between the HIS4 gene product of Saccharomyces cerevisiae and the hisIE and hisD gene products of Escherichia coli and Salmonella typhimurium
- Alterations in the Two Globular Domains or in the Connecting α-Helix of Bacterial Ribosomal Protein L9 Induces +1 Frameshifts
- Possible regulation of the Salmonella typhimurium histidine operon by adenosine triphosphate phosphoribosyltransferase: large metabolic effects
- Genetic fusions for operon analysis.
- Allosteric Regulation of the First Enzyme in Histidine Biosynthesis
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