Interaction between heat shock factor and hsp70 is insufficient to suppress induction of DNA-binding activity in vivo
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Summary
The level of heat shock proteins may affect the rate of disassembly of HSF trimers, but another mechanism, as yet undefined, appears to control the onset of the oligomeric transitions.
- Type
- article
- Published
- 1994-10-01
- Cited by
- 161
- References
- 58
- Access
- Open access
- OpenAlex
- https://openalex.org/W1912190980
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19176039
Keywords
Hsp70, Heat shock protein, Heat shock factor, Biology, HSPA4
References
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- The DNA-binding activity of the human heat shock transcription factor is regulated in vivo by hsp70
- The yeast heat shock transcription factor contains a transcriptional activation domain whose activity is repressed under nonshock conditions.
- Fine structure analyses of the Drosophila and Saccharomyces heat shock factor--heat shock element interactions.
- Heat‐induced transcription from RNA polymerases II and III and HSF binding activity are co‐ordinately regulated by the products of the heat shock genes
- Induction temperature of human heat shock factor is reprogrammed in a Drosophila cell environment
- Activating protein factor binds in vitro to upstream control sequences in heat shock gene chromatin
- Trimerization of a yeast transcriptional activator via a coiled-coil motif.
- Yeast heat shock factor contains separable transient and sustained response transcriptional activators.
- The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels.
- Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene.
Cited by
- Chromosomes and expression mechanisms
- Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease.
- How Cells Protect Themselves against Stress?
- Heat shock protein expression in fish
- Transcriptional regulation of the metazoan stress protein response.
- Sensing stress and responding to stress.
- The role of protein phosphatase 5 (PP5) in the regulation of heat shock factor 1 (HSF1) in xenopus laevis oocytes
- Chaperone regulation of the heat shock protein response.
- Role and regulatory mechanisms of heat shock factor 2
- Analysis of Heat Shock Proteins and Thermotolerance in a Thermoresistant Strain of Drosophila melanogaster
- Regulation of the heat shock response by thiol-reactive compounds in the yeast Saccharomyces cerevisiae
- Defence of Agaricus bisporus against toxic secondary metabolites from Trichoderma aggressivum.
- Overexpression of HSP‐70 inhibits the phosphorylation of HSF1 by activating protein phosphatase and inhibiting protein kinase C activity
- Investigation of the Hsp90 C-terminal Binding Site, Novel Inhibitors and Isoform-Dependent Client Proteins
- Fever, Immunity, and Molecular Adaptations
- Regulation of the members of the mammalian heat shock factor family
- Molecular aspects of the stress response : chaperones, membranes and networks
- Regulation of heat shock factor 1 (HSF1) DNA-binding and transcription
- Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes Kv1.5 channels in HL-1 cells
- Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.
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