Ischemic and anesthetic preconditioning reduces cytosolic [Ca2+] and improves Ca(2+) responses in intact hearts.
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Summary
Both SPC and IPC similarly reduce Ca( 2+) loading, while augmenting contractile responsiveness to Ca(2+), improving postischemia cardiac function and attenuating permanent damage.
- Type
- article
- Published
- 2001-10-01
- Cited by
- 97
- References
- 58
- OpenAlex
- https://openalex.org/W1910890390
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25243018
Keywords
Ischemia, Ischemic preconditioning, Diastole, Anesthesia, Chemistry
References
- The transient nature of the effect of ischemic preconditioning on myocardial infarct size and ventricular arrhythmia.
- Protein kinase C. Its role in ischemic preconditioning in the rat.
- Prior preconditioning by ischemia or sevoflurane improves cardiac work per oxygen use in isolated guinea pig hearts after global ischemia.
- Modification of myofibrillar responsiveness to Ca++ as an inotropic mechanism.
- Attenuation of postischemic reperfusion injury is related to prevention of [Ca2+]m overload in rat hearts.
- Mechanisms of ischemic preconditioning effects on Ca(2+) paradox-induced changes in heart.
- Ischemic preconditioning triggers tyrosine kinase signaling: a potential role for MAPKAP kinase 2.
- Changes in intracellular Na+ and pH in rat heart during ischemia: role of Na+/H+ exchanger.
- Improved myocardial ischemic response and enhanced collateral circulation with long repetitive coronary occlusion during angioplasty: a prospective study.
- Investigation of factors affecting fluorometric quantitation of cytosolic [Ca2+] in perfused hearts.
- Phosphorylation Specificities of Protein Kinase C Isozymes for Bovine Cardiac Troponin I and Troponin T and Sites within These Proteins and Regulation of Myofilament Properties*
- Protection Against Infarction Afforded by Preconditioning is Mediated by A1 Adenosine Receptors in Rabbit Heart
- INCREASES IN MITOCHONDRIAL FREE Ca2+ DURING AND AFTER ISCHEMIA ARE UNALTERED BY SEVOFLURANE OR ISCHEMIC PRECONDITIONING IN ISOLATED HEARTS
- Halothane Reduces Release of Adenosine, Inosine, and Lactate with Ischemia and Reperfusion in Isolated Hearts
- Isoflurane Mimics Ischemic Preconditioning via Activation of KATP Channels: Reduction of Myocardial Infarct Size with An Acute Memory Phase
- SEVOFLURANE OR ISCHEMIC PRECONDITIONING DO NOT ALTER MITOCHONDRIAL [Ca (2+)] ELEVATION BY EXTERNAL CALCIUM BEFORE OR AFTER ISCHEMIA IN ISOLATED HEARTS
- Relationship between intracellular calcium and contractile force in stunned myocardium. Direct evidence for decreased myofilament Ca2+ responsiveness and altered diastolic function in intact ventricular muscle.
- Sevoflurane mimics ischemic preconditioning effects on coronary flow and nitric oxide release in isolated hearts.
- Isoflurane, but not Halothane, Induces Protection of Human Myocardium via Adenosine A1 Receptors and Adenosine Triphosphate–sensitive Potassium Channels
- Mechanisms of isoflurane-induced myocardial preconditioning in rabbits.
Cited by
- ERK-MAPK Signaling Opposes Rho-Kinase to Reduce Cardiomyocyte Apoptosis in Heart Ischemic Preconditioning
- Mechanism of Cardiac Preconditioning with Volatile Anaesthetics
- Rho-kinase inhibition is involved in the activation of PI3-kinase/Akt during ischemic-preconditioning-induced cardiomyocyte apoptosis.
- Cardiac Preconditioning by Anesthetic Agents: Roles of Volatile Anesthetics and Opioids in Cardioprotection
- Myocardial protection by pre- and post-anesthetic conditioning.
- Preconditioning with Sevoflurane Reduces Changes in Nicotinamide Adenine Dinucleotide during Ischemia–Reperfusion in Isolated Hearts: Reversal by 5-Hydroxydecanoic Acid
- Inflammatory response and cardioprotection during open‐heart surgery: the importance of anaesthetics
- In Vivo Desflurane Preconditioning Evokes Dynamic Alterations of Metabolic Proteins in the Heart - Proteomic Insights Strengthen the Link between Bioenergetics and Cardioprotection
- Anesthetic preconditioning versus anesthetic treatment: effects on ischemic injury in isolated hearts.
- Cardiotonic drugs differentially alter cytosolic [Ca2+] to left ventricular relationships before and after ischemia in isolated guinea pig hearts.
- Myocardial Protection by Isoflurane Preconditioning Preserves Ca2+ Cycling Proteins Independent of Sarcolemmal and Mitochondrial KATP Channels
- ANESTHETIC PRECONDITIONING CONFERS ACUTE CARDIOPROTECTION VIA UP-REGULATION OF MANGANESE SUPEROXIDE DISMUTASE AND PRESERVATION OF MITOCHONDRIAL RESPIRATORY ENZYME ACTIVITY
- Sevoflurane Preconditioning Limits Intracellular/Mitochondrial Ca2+ in Ischemic Newborn Myocardium
- Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes.
- Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury.
- Mitochondria and Arrhythmias
- Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning.
- Reduced Efficacy of Volatile Anesthetic Preconditioning with Advanced Age in Isolated Rat Myocardium
- Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts.
- Accelerated inactivation of cardiac L‐type calcium channels triggered by anaesthetic‐induced preconditioning
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