Integrin receptor imaging of breast cancer: a proof-of-concept study to evaluate 99mTc-NC100692.
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Summary
Overall, the efficacy data in subjects with suspected breast lesions suggest that (99m)Tc-NC100692 scintigraphy may be effective in detecting malignant lesions.
- Type
- article
- Published
- 2006-09-01
- Cited by
- 120
- References
- 21
- OpenAlex
- https://openalex.org/W1909948732
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25317805
Keywords
Medicine, Histopathology, Breast cancer, Scintigraphy, Adverse effect
References
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- Angiogenesis and apoptosis.
- Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction.
- Comparative evaluation of linear and cyclic 99mTc-RGD peptides for targeting of integrins in tumor angiogenesis.
- Targeting tumor angiogenesis: comparison of peptide and polymer-peptide conjugates.
- 99mTc-sestamibi uptake and histological malignancy grade in invasive breast carcinoma
- Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model.
- Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics.
- Angiogenesis: basic pathophysiology and implications for disease.
- Prediction of the usefulness of combined mammography and scintimammography in suspected primary breast cancer using ROC curves.
- Prone scintimammography in patients with suspicion of carcinoma of the breast.
Cited by
- Preclinical Molecular Imaging of Tumor Angiogenesis
- Integrin Imaging with 99mTc-3PRGD2 SPECT/CT Shows High Specificity in the Diagnosis of Lymph Node Metastasis from Non-Small Cell Lung Cancer.
- Molecular imaging and the failing heart: through the looking glass.
- 18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2): synthesis and microPET imaging of αvβ3 integrin expression
- Study of novel molecular probe 99mTc-3PRGD2 in the diagnosis of rheumatoid arthritis
- Elucidating the IGFBP2 signaling pathway in glioma development and progression
- Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review
- Integrin αvβ3 as a Promising Target to Image Neoangiogenesis Using In-House Generator-Produced Positron Emitter 68Ga-Labeled DOTA-Arginine-Glycine-Aspartic Acid (RGD) Ligand
- Molecular breast imaging
- 99mTc-3PRGD2 SPECT/CT predicts the outcome of advanced nonsquamous non-small cell lung cancer receiving chemoradiotherapy plus bevacizumab
- Radiopharmaceutical development of radiolabelled peptides
- Imagerie de la néoangiogenèse en médecine nucléaire
- Metabolism in rats of NC100692, an RGD-peptide for imaging of angiogenesis.
- Clinical feasibility study to detect angiogenesis following bone marrow stem cell transplantation in chronic ischaemic heart failure
- Methods for 18F-labeling of RGD peptides: comparison of aminooxy [18F]fluorobenzaldehyde condensation with ‘click labeling’ using 2-[18F]fluoroethylazide, and S-alkylation with [18F]fluoropropanethiol
- Non-Invasive Imaging for Studying Anti-Angiogenic Therapy Effects
- Molecular imaging of angiogenesis with SPECT
- The Biodistribution and Radiation Dosimetry of the Arg-Gly-Asp Peptide 18F-AH111585 in Healthy Volunteers
- Molecular imaging targeting peptide receptors.
- Multimodality Imaging of Integrin αvβ3 Expression
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