Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulence

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Summary

This study demonstrated that macrophage tropism alone is not sufficient for the development of neurological disease and showed that additional sequences derived from the transmembrane portion of envelope and/or nef confer neurovirulence.

Type
article
Published
1997-08-01
Cited by
154
References
24
Access
Open access

Keywords

Virology, Simian immunodeficiency virus, Biology, Tropism, Tissue tropism

References

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