Two mutations which affect the barrier function of the Escherichia coli K-12 outer membrane

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Summary

Two genetically distinct classes of novobiocin-supersensitive mutants were isolated from Escherichia coli K-12, showing increased sensitivity to hydrophobic drugs but are different: NbsA cells tend to be more sensitive to cationic agents, whereas NbsB cells show the opposite tendency.

Type
article
Published
1979-09-01
Cited by
136
References
58
Access
Open access

Keywords

Biology, Escherichia coli, Mutant, Complementation, Lipopolysaccharide

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