A Dual Role for NOTCH Signaling in Joint Cartilage Maintenance and Osteoarthritis

Keywords

Notch signaling pathway, Osteoarthritis, Context (archaeology), Cartilage, Joint (building)

References

• Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes.Florenzo Iannone — 2002
• RBPjκ-dependent Notch signaling is required for articular cartilage and joint maintenanceAnthony J. Mirando, Zhaoyang Liu, Tyler C. Moore — 2013
• Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors.J.-P. Pelletier, V Lascau-Coman, Dragan Jovanović — 1999
• Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline inductionGusztáv Bélteki — 2005
• Expression patterns of Notch receptors and their ligands in human osteoarthritic and healthy articular cartilage.Moe R. Mahjoub, Nadia Sassi, Maha Driss — 2012
• The role of the cartilage matrix in osteoarthritisDick Heinegård, Tore Saxne — 2011
• Direct regulation of intestinal fate by Notch.Ben Z. Stanger, Radhika Datar, L. Charles Murtaugh — 2005
• The immunohistochemical localization of notch receptors and ligands in human articular cartilage, chondroprogenitor culture and ultrastructural characteristics of these progenitor cells.İsmail Üstünel, A. Merter Özenci, Zeliha Sahin — 2008
• Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis developmentYoko Hosaka, Taku Saito, Shurei Sugita — 2013
• The Canonical Notch Signaling Pathway: Unfolding the Activation MechanismRaphael Kopan, Ma. Xenia G. Ilagan — 2009
• Nitric oxide in osteoarthritis.R. Studer, Daniel Jaffurs, Maja Stefanović-Račić — 1999
• Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford studyGregory Livshits, Guangju Zhai, Deborah Hart — 2009
• Suppression of differentiation and proliferation of early chondrogenic cells by NotchNaoko Watanabe, Yoko Tezuka, Kenji Matsuno — 2003
• Direct regulation of interleukin-6 expression by Notch signaling in macrophagesWipawee Wongchana, Tanapat Palaga — 2011
• The distribution of Notch receptors and their ligands during articular cartilage developmentAnthony J. Hayes, G. P. Dowthwaite, S. Webster — 2003
• Notch1 signaling regulates chondrogenic lineage determination through Sox9 activationR Haller, Ralf Schwanbeck, Simone Martini — 2011
• Insights from human genetic studies into the pathways involved in osteoarthritisLouise N. Reynard, John Loughlin — 2013
• Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritisShawn P. Grogan, Shigeru Miyaki, Hiroshi Asahara — 2009
• The individual and socioeconomic impact of osteoarthritisDavid J. Hunter, Deborah Schofield, Emily Callander — 2014
• Osteoarthritis development in novel experimental mouse models induced by knee joint instability.Satoru Kamekura, Kazuto Hoshi, Takashi Shimoaka — 2005

Cited by

• A top-notch dilemma: The complex role of NOTCH signaling in osteoarthritisA. Ratneswaran, Frank Beier — 2015
• Notch Signaling in Postnatal Joint Chondrocytes, but not Subchondral Osteoblasts, is Required for Articular Cartilage and Joint MaintenanceZhaoyang Liu, Yinshi Ren, Anthony J. Mirando — 2015
• Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritisNeng‐Yu Lin, Alfiya Distler, Christian Beyer — 2016
• Novel therapeutic targets in osteoarthritis: Narrative review on knock-out genes involved in disease development in mouse animal models.Francesca Veronesi, Elena Della Bella, Simona Cepollaro — 2016
• Notch Signaling and the Skeleton.Stefano Zanotti, Ernesto Canalis — 2016
• HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage developmentTimothy P. Rutkowski, Anat Kohn, Deepika Sharma — 2016
• Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrestXifu Shang, Jinwu Wang, Zhengliang Luo — 2016
• Building and maintaining joints by exquisite local control of cell fateJoanna Smeeton, Amjad Askary, J. Gage Crump — 2016
• Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritisAugustin Latourte, C. Cherifi, Jérémy Maillet — 2016
• A Whole Exome Study Identifies Novel Candidate Genes for Vertebral Bone Marrow Signal Changes (Modic Changes)Minna Kraatari‐Tiri, Sini Skarp, Jaakko Niinimäki — 2017
• LC-MS/MS analysis and evaluation of the anti-inflammatory activity of components from BushenHuoxue decoctionDongdong Sun, Qiuying Yan, Xiaofang Xu — 2017
• Notch signaling mediated by TGF-β/Smad pathway in concanavalin A-induced liver fibrosis in ratsYi Wang, Ruowu Shen, Bing Han — 2017
• Dwarfism in Homozygous Agc1CreERT Mice is Associated with Decreased Expression of AggrecanHarunur Rashid, Haiyan Chen, Quamarul Hassan — 2017
• Knockdown MiR-302b Alleviates LPS-Induced Injury by Targeting Smad3 in C28/I2 Chondrocytic CellsYue-sheng Wang, Tao Yu, Hui Jin — 2018
• LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 ChondrocytesFeng Li, Jianguang Sun, Shilei Huang — 2018
• Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular PathogenesisJu‐Ryoung Kim, Jong Jin Yoo, Hyun Kim — 2018
• Evidence that miR‐146a attenuates aging‐ and trauma‐induced osteoarthritis by inhibiting Notch1, IL‐6, and IL‐1 mediated catabolismY GUAN, Jing Li, Xu Yang — 2018
• Cell type-specific effects of Notch signaling activation on intervertebral discs: Implications for intervertebral disc degenerationYixin Zheng, Cunchang Liu, Li Ni — 2018
• Inhibition of notch signaling pathway temporally postpones the cartilage degradation progress of temporomandibular joint arthritis in mice.Xueting Luo, Yangmei Jiang, Ruiye Bi — 2018
• MICE HARBORING A HAJDU CHENEY SYNDROME MUTATION ARE SENSITIZED TO OSTEOARTHRITISStefano Zanotti, Jungeun Yu, Dr Caroline Bridgewater — 2018

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