Chemokine polyreactivity of IL7Rα+CSF-1R+ lympho-myeloid progenitors in the developing fetal liver

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Summary

It is proposed that chemokine polyreactive, cytokine-bipotent and monopotent progenitors transmigrate through LYVE-1high endothelium, attracted by selected chemokines and reach the IL7- and CSF-1-producing ALCAMhigh mesenchymal niche, attract by other sets of chemokites, to differentiate to B-lymphoid respectively myeloid cells.

Type
article
Published
2015-08-03
Cited by
12
References
59
Access
Open access

Keywords

Myeloid, Biology, Interleukin-7 receptor, Immunology, Chemokine receptor

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