Lack of beta-catenin affects mouse development at gastrulation.
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Summary
It is demonstrated that, although beta-catenin is expressed rather ubiquitously, it is specifically required in the ectodermal cell layer, as it binds to the cytoplasmic domain of E-cadherin and to alpha-Catenin.
- Type
- article
- Published
- 1995-11-01
- Cited by
- 759
- References
- 55
- OpenAlex
- https://openalex.org/W1886443720
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1506770
Keywords
Biology, Ectoderm, Cell biology, Mesoderm, Gastrulation
References
- A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.
- The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.
- Identification of a putative cell adhesion domain of uvomorulin.
- Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes
- Cloning and characterization of SRP1, a suppressor of temperature-sensitive RNA polymerase I mutations, in Saccharomyces cerevisiae
- Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the beta-catenin gene in a human cancer cell line, HSC-39
- Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.
- Essential role of Mash-2 in extraembryonic development
- Association of the APC tumor suppressor protein with catenins.
- Overexpression of cadherins and underexpression of β-catenin inhibit dorsal mesoderm induction in early Xenopus embryos
- Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein.
- Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells.
- Cadherin cell adhesion receptors as a morphogenetic regulator.
- Molecular organization of the uvomorulin-catenin complex
- Gene regulation: translational initiation by internal ribosome binding
- Stage-specific response of preimplantation mouse embryos to W-7, a calmodulin antagonist.
- Fast screening of mouse mutants generated after homologous recombination.
- A repeating amino acid motif shared by proteins with diverse cellular roles.
- Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.
- From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion.
Cited by
- Composition, regulation, and function of the cytoskeleton in mammalian eggs and embryos.
- Skeletal development--Wnts are in control.
- Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart
- E-cadherin regulates cell growth by modulating proliferation-dependent β-catenin transcriptional activity
- Maintenance of the Epithelial Barrier in a Bronchial Epithelial Cell Line is Dependent on Functional E-cadherin Local to the Tight Junctions
- Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge.
- Adherens junctions and cancer.
- β‐catenin–mediated cell‐adhesion is vital for embryonic forebrain development
- β-Catenin is essential for Müllerian duct regression during male sexual differentiation
- Signaling from the Adherens Junction
- Wnt/β-catenin signaling pathway safeguards epigenetic stability and homeostasis of mouse embryonic stem cells
- Humans and mice with prickle mutations show a propensity for epilepsy and display autism-like behaviors with evidence for hippocampal synaptic dysfunction
- Epithelial Cell Shape Changes During Lung Branching Morphogenesis: The Role of Wnt/Fzd2 signaling in directing new branch formation
- The Control of β-catenin and TCF During Embryonic Development and Cancer
- Modulating the Transcriptional Activity of Beta-Catenin During the Osteogenic Differentiation of Embryonic Stem Cells
- High-thoughput Screen to Identify Small Molecule Inhibitors of the Canonical Wnt Signaling Pathway
- Differentiation of definitive endoderm from mouse embryonic stem cells.
- Contribution of the canonical Wnt pathway in Tribolium anterior-posterior axis patterning
- The story of redundant catenins and their roles in cell-cell adhesion in the liver
- Transcriptional Integration of Wnt and Nodal Signals in the Establishment of the Spemann Organizer
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