Transduction of psychosocial stress into the neurobiology of recurrent affective disorder.
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Summary
The author postulates that both sensitization to stressors and episode sensitization occur and become encoded at the level of gene expression, suggesting that the biochemical and anatomical substrates underlying the affective disorders evolve over time as a function of recurrences, as does pharmacological responsivity.
- Type
- review
- Published
- 1992-08-01
- Cited by
- 1,836
- References
- 99
- OpenAlex
- https://openalex.org/W1881281756
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20286681
Keywords
Stressor, Psychosocial, Psychology, Sensitization, Psychiatry
References
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- Advances in understanding major depressive disorder.
- Adrenoceptor antagonists block c-fos response to stress in the mouse brain.
- Adrenal function predicts demoralization after losses.
- Developmental lead exposure in rats: is a behavioral sequel extended at F2 generation?
- Morphological alterations of neurons and astrocytes and changes in emotional behavior in pentylenetetrazol-kindled rats.
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- Intensification of cataleptic response in 6‐hydroxydopamine‐induced neurodegeneration of substantia nigra is not dependent on the degree of dopamine depletion
- Course and outcome of bipolar spectrum disorder in children and adolescents: A review of the existing literature
- Biopsychosocial model in Depression revisited.
- African American Children’s Depressive Symptoms: The Prospective Effects of Neighborhood Disorder, Stressful Life Events, and Parenting
- Modulation of stress consequences by hippocampal monoaminergic, glutamatergic and nitrergic neurotransmitter systems
- Sex, stressful life events, and adult onset depression and alcohol dependence: are men and women equally vulnerable?
- Recurrence in major depression: a conceptual analysis.
- The Clinical Implications Of Cognitive Impairment and Allostatic Load in Bipolar Disorder
- Neurotransmitters and neuropeptides in depression.
- Child neglect and trauma: The additive traumatic effects of neglect on maltreated adolescents
- What is the contribution of different cognitive biases and stressful childhood events to the presence and number of previous depressive episodes?
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