Carboxyfullerene neuroprotection post injury in parkinsonian nonhuman primates
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Summary
C3 is a first‐in‐class functionalized water‐soluble fullerene that reduces oxygen radical species associated with neurodegeneration in in vitro studies, but has not been evaluated as a neuroprotective agent in a Parkinson model in vivo.
- Type
- article
- Published
- 2014-07-22
- Cited by
- 65
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W1871866084
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17914694
Keywords
MPTP, Parkinsonism, Vesicular monoamine transporter, Dopamine, Neuroprotection
References
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- Distinct Mechanisms Underlie Neurotoxin-Mediated Cell Death in Cultured Dopaminergic Neurons
- Validation of nigrostriatal PET measures: critical limits
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- No Differential Regulation of Dopamine Transporter (DAT) and Vesicular Monoamine Transporter 2 (VMAT2) Binding in a Primate Model of Parkinson Disease
- Carboxyfullerenes as neuroprotective agents.
- A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties.
- Cerebral Mitochondrial Metabolism in Early Parkinson's Disease
- A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice.
- Registration of [18F]FDG microPET and small-animal MRI.
- Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Generalizations
- Distribution Volume Ratios without Blood Sampling from Graphical Analysis of PET Data
- Ketamine-Induced Loss of Phenotype of Fast-Spiking Interneurons Is Mediated by NADPH-Oxidase
- Interleukin-6 Mediates the Increase in NADPH-Oxidase in the Ketamine Model of Schizophrenia
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced acute transient dystonia in monkeys associated with low striatal dopamine.
- Dopamine pathway loss in nucleus accumbens and ventral tegmental area predicts apathetic behavior in MPTP-lesioned monkeys
- Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data
- Parkinson's disease: genetics and pathogenesis.
- Low Nigrostriatal Reserve for Motor Parkinsonism in Nonhuman Primates
Cited by
- Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions.
- Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes.
- Neuroprotective effects of piperine on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease mouse model.
- Human induced pluripotent stem cells in Parkinson's disease: A novel cell source of cell therapy and disease modeling.
- Physico-chemical properties of the water-soluble C70-tris-malonic solutions
- Carbon Nanomaterials Interfacing with Neurons: An In vivo Perspective
- Water-soluble fullerenes for medical applications
- Inhibition of Reactive Gliosis in the Retina of Rats with Streptozotocin-Induced Diabetes under the Action of Hydrated C60 Fullerene
- Carboxyfullerene nanoparticles alleviate acute hepatic injury in severe hemorrhagic shock.
- The MPTP Story
- PEGylation corannulene enhances response of stress through promoting neurogenesis.
- Non-human primate models of PD to test novel therapies
- Carboxylated fullerenes: Physico-chemical properties and potential applications
- 7T MRI subthalamic nucleus atlas for use with 3T MRI
- Integrated nanozymes: facile preparation and biomedical applications.
- Pharmacokinetics and toxicology of the neuroprotective e,e,e-methanofullerene(63)-carboxylic acid in mice and primates
- Water Soluble Nanocarbon Materials:A Panacea for All?
- In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
- FULLERENECARBOXYLIC ACIDS AND PROSPECTS FOR THEIR USE IN THE CHEMISTRY OF DRUGS
- Reduction of Leukocyte Microvascular Adherence and Preservation of Blood-Brain Barrier Function by Superoxide-Lowering Therapies in a Piglet Model of Neonatal Asphyxia
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